FOG01818
EOG8WH71J

sce:GDB1

Genes: 30

SGD Description
Glycogen debranching enzyme; contains glucanotranferase and alpha-1,6-amyloglucosidase activities; required for glycogen degradation; phosphorylated in mitochondria; activity is inhibited by Igd1p; protein abundance increases in response to DNA replication stress


AspGD Description
Glycogen debranching enzyme; 1,3-alpha-glucan synthase


References

Teste MA, et al. (2000 Dec 1). The Saccharomyces cerevisiae YPR184w gene encodes the glycogen debranching enzyme.

Nakayama A, et al. (2000 Jul). High expression of glycogen-debranching enzyme in Escherichia coli and its competent purification method.

Reinders J, et al. (2007 Nov). Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase.

Coutinho PM, et al. (2009 Mar). Post-genomic insights into the plant polysaccharide degradation potential of Aspergillus nidulans and comparison to Aspergillus niger and Aspergillus oryzae.

Walkey CJ, et al. (2011 Sep). The Saccharomyces cerevisiae fermentation stress response protein Igd1p/Yfr017p regulates glycogen levels by inhibiting the glycogen debranching enzyme.

Zhai L, et al. (2016 Apr 18). Crystal structure of glycogen debranching enzyme and insights into its catalysis and disease-causing mutations.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
18 genes with posterior transmembrane prediction > 50%