FOG01749
EOG8BNZSN

sce:ROT2

Genes: 35

SGD Description
Glucosidase II catalytic subunit; required for normal cell wall synthesis; mutations in rot2 suppress tor2 mutations, and are synthetically lethal with rot1 mutations


PomBase Description
glucosidase II alpha subunit Gls2


AspGD Description
Alpha-glucosidase; ER glucosidase II alpha subunit; expression enhanced by maltose


References

Saunier B, et al. (1982 Dec 10). Inhibition of N-linked complex oligosaccharide formation by 1-deoxynojirimycin, an inhibitor of processing glucosidases.

Trombetta ES, et al. (1996 Nov 1). Endoplasmic reticulum glucosidase II is composed of a catalytic subunit, conserved from yeast to mammals, and a tightly bound noncatalytic HDEL-containing subunit.

Wilkinson BM, et al. (2006 Mar 10). Yeast GTB1 encodes a subunit of glucosidase II required for glycoprotein processing in the endoplasmic reticulum.

Coutinho PM, et al. (2009 Mar). Post-genomic insights into the plant polysaccharide degradation potential of Aspergillus nidulans and comparison to Aspergillus niger and Aspergillus oryzae.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
1 genes with posterior transmembrane prediction > 50%