FOG01730
EOG8J9KF5
EOG8M6403

sce:IMA2;IMA5;MAL12;MAL32;IMA3;IMA1;IMA4

Genes: 60

Protein description
maltase


SGD Description
Isomaltase (alpha-1,6-glucosidase/alpha-methylglucosidase); preferred specificity for isomaltose, alpha-methylglucoside, and palatinose, but also exhibits alpha-1,2 glucosidase activity on sucrose and kojibiose, and can cleave the 1,3-alpha linkage of nigerose and turanose and the alpha-1,5 linkage of leucrose in vitro; not required for isomaltose utilization, but Ima2p overexpression allows the ima1 null mutant to grow on isomaltose|Alpha-glucosidase; specificity for isomaltose, maltose, and palatinose, but not alpha-methylglucoside; most distant member of the IMA isomaltase family, but with similar catalytic properties as Ima1p and Ima2p; not required for isomaltose utilization, but Ima5p overexpression allows the ima1 null mutant to grow on isomaltose; can cleave alpha-1,3 linkage of nigerose and turanose and alpha-1,5 linkage of leucrose and is very sensitive to temperature in vitro|Maltase (alpha-D-glucosidase); inducible protein involved in maltose catabolism; encoded in the MAL1 complex locus; hydrolyzes the disaccharides maltose, turanose, maltotriose, and sucrose|Maltase (alpha-D-glucosidase); inducible protein involved in maltose catabolism; encoded in the MAL3 complex locus; functional in genomic reference strain S288C; hydrolyzes the disaccharides maltose, turanose, maltotriose, and sucrose|Alpha-glucosidase; weak, but broad substrate specificity for alpha-1,4- and alpha-1,6-glucosides; member of IMA isomaltase family; not required for isomaltose utilization, but Ima3p overexpression allows the ima1 null mutant to grow on isomaltose; lower activitiy and thermostability in vitro than Ima2p despite sequence difference of only 3 amino acids; cleaves alpha-1,3 linkage of nigerose and turanose, but not alpha-1,5 of leucrose; identical to IMA4|Major isomaltase (alpha-1,6-glucosidase/alpha-methylglucosidase); required for isomaltose utilization; preferred specificity for isomaltose, alpha-methylglucoside, and palatinose, but also exhibits alpha-1,2 glucosidase activity on sucrose and kojibiose, and can cleave the 1,3-alpha linkage of nigerose and turanose and the alpha-1,5 linkage of leucrose in vitro; member of the IMA isomaltase family|Alpha-glucosidase; weak, but broad substrate specificity for alpha-1,4- and alpha-1,6-glucosides; member of IMA isomaltase family; not required for isomaltose utilization, but Ima4p overexpression allows the ima1 null mutant to grow on isomaltose; identical to IMA3


PomBase Description
maltase alpha-glucosidase Mal1


AspGD Description
Putative alpha-glucosidase|Putative alpha-glucosidase


References

Alexandre H, et al. (2001 Jun 1). Global gene expression during short-term ethanol stress in Saccharomyces cerevisiae.

Hikkel I, et al. (2003 Mar 28). A general strategy to uncover transcription factor properties identifies a new regulator of drug resistance in yeast.

Sickmann A, et al. (2003 Nov 11). The proteome of Saccharomyces cerevisiae mitochondria.

Yamamoto K, et al. (2004 Aug). Val216 decides the substrate specificity of alpha-glucosidase in Saccharomyces cerevisiae.

David H, et al. (2006). Metabolic network driven analysis of genome-wide transcription data from Aspergillus nidulans.

Reinders J, et al. (2006 Jul). Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

Bauer S, et al. (2006 Jul 25). Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

Nakamura T, et al. (2006 Oct). Expression profile of amylolytic genes in Aspergillus nidulans.

Coutinho PM, et al. (2009 Mar). Post-genomic insights into the plant polysaccharide degradation potential of Aspergillus nidulans and comparison to Aspergillus niger and Aspergillus oryzae.

Teste MA, et al. (2010 Aug 27). Characterization of a new multigene family encoding isomaltases in the yeast Saccharomyces cerevisiae, the IMA family.

Hasegawa S, et al. (2010 Jan). Characterization and expression analysis of a maltose-utilizing (MAL) cluster in Aspergillus oryzae.

Yamamoto K, et al. (2010 Oct). Crystal structures of isomaltase from Saccharomyces cerevisiae and in complex with its competitive inhibitor maltose.

Viigand K, et al. (2016 Aug). Maltase protein of Ogataea (Hansenula) polymorpha is a counterpart to the resurrected ancestor protein ancMALS of yeast maltases and isomaltases.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 10 genes with posterior transmembrane prediction > 50%

FOG01731
EOG82JM76
EOG8M6403

sce:absent

Genes: 14

PomBase Description
alpha-amylase homolog (predicted)|alpha-amylase homolog Aah2 (predicted)|alpha-amylase homolog Aah3|alpha-amylase homolog Mde5


AspGD Description
Alpha-amylase|Alpha-amylase (1, 4-alpha-D-glucan 4-glucanohydrolase), hydrolyzes the alpha-1,4-glucosidic bonds in glycogen or starch; identical to An12g06930; AmyR-regulated|Putative acid alpha-amylase; abundantly expressed on d-maltose; most highly expressed at the periphery of colonies; repressed by xylose and induced by maltose; AmyR dependant regulation


References

Fujii I, et al. (1996 Nov 27). Cloning of the polyketide synthase gene atX from Aspergillus terreus and its identification as the 6-methylsalicylic acid synthase gene by heterologous expression.

Kanemori Y, et al. (1999 Jan). Insertion analysis of putative functional elements in the promoter region of the Aspergillus oryzae Taka-amylase A gene (amyB) using a heterologous Aspergillus nidulans amdS-lacZ fusion gene system.

De Groot PW, et al. (2003 Jul 15). Genome-wide identification of fungal GPI proteins.

Morita T, et al. (2006 Jun). An alpha-amylase homologue, aah3, encodes a GPI-anchored membrane protein required for cell wall integrity and morphogenesis in Schizosaccharomyces pombe.

Nakamura T, et al. (2006 Oct). Expression profile of amylolytic genes in Aspergillus nidulans.

Kennedy PJ, et al. (2008 Nov). A genome-wide screen of genes involved in cadmium tolerance in Schizosaccharomyces pombe.

Coutinho PM, et al. (2009 Mar). Post-genomic insights into the plant polysaccharide degradation potential of Aspergillus nidulans and comparison to Aspergillus niger and Aspergillus oryzae.

de Groot PW, et al. (2009 Mar). Comprehensive genomic analysis of cell wall genes in Aspergillus nidulans.

Cao W, et al. (2009 Oct). Using a new GPI-anchored-protein identification system to mine the protein databases of Aspergillus fumigatus, Aspergillus nidulans, and Aspergillus oryzae.

Kojima T, et al. (2010 Jun). High-throughput screening of DNA binding sites for transcription factor AmyR from Aspergillus nidulans using DNA beads display system.

Amorim MJ, et al. (2010 Jun 8). Global coordination of transcriptional control and mRNA decay during cellular differentiation.

Arita Y, et al. (2011 May). Microarray-based target identification using drug hypersensitive fission yeast expressing ORFeome.

Jaiseng W, et al. (2012). Studies on the roles of clathrin-mediated membrane trafficking and zinc transporter Cis4 in the transport of GPI-anchored proteins in fission yeast.

Fang Y, et al. (2012 Apr). A genomewide screen in Schizosaccharomyces pombe for genes affecting the sensitivity of antifungal drugs that target ergosterol biosynthesis.

Pan X, et al. (2012 Nov 23). Identification of novel genes involved in DNA damage response by screening a genome-wide Schizosaccharomyces pombe deletion library.

Chen Z, et al. (2012 Oct). A genetic screen to discover pathways affecting cohesin function in Schizosaccharomyces pombe identifies chromatin effectors.

Sun LL, et al. (2013). Global analysis of fission yeast mating genes reveals new autophagy factors.

Hunter AJ, et al. (2013 Sep). Deletion of creB in Aspergillus oryzae increases secreted hydrolytic enzyme activity.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Graml V, et al. (2014 Oct 27). A genomic Multiprocess survey of machineries that control and link cell shape, microtubule organization, and cell-cycle progression.

Malecki M, et al. (2016 Nov 25). Functional and regulatory profiling of energy metabolism in fission yeast.

Guo L, et al. (2016 Oct 13). Global Fitness Profiling Identifies Arsenic and Cadmium Tolerance Mechanisms in Fission Yeast.

Lee J, et al. (2017 Feb 20). Chromatin remodeller Fun30^Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 5 genes with posterior transmembrane prediction > 50%

FOG01732
EOG8M6403

sce:absent

Genes: 2

AspGD Description
GPI-anchored alpha-glucanosyltransferase; alpha-glucan transferase; induced by caspofungin|Alpha-glucanotransferase; alpha-amylase


References

Nakamura T, et al. (2006 Oct). Expression profile of amylolytic genes in Aspergillus nidulans.

Coutinho PM, et al. (2009 Mar). Post-genomic insights into the plant polysaccharide degradation potential of Aspergillus nidulans and comparison to Aspergillus niger and Aspergillus oryzae.

de Groot PW, et al. (2009 Mar). Comprehensive genomic analysis of cell wall genes in Aspergillus nidulans.

Cao W, et al. (2009 Oct). Using a new GPI-anchored-protein identification system to mine the protein databases of Aspergillus fumigatus, Aspergillus nidulans, and Aspergillus oryzae.

Hunter AJ, et al. (2013 Sep). Deletion of creB in Aspergillus oryzae increases secreted hydrolytic enzyme activity.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%

FOG01733
EOG866T4K
EOG8N2Z6B

sce:absent

Genes: 7

AspGD Description
Putative endo-glucanase; secreted protein


References

Bok JW, et al. (2006 Jan). Genomic mining for Aspergillus natural products.

Bauer S, et al. (2006 Jul 25). Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

Coutinho PM, et al. (2009 Mar). Post-genomic insights into the plant polysaccharide degradation potential of Aspergillus nidulans and comparison to Aspergillus niger and Aspergillus oryzae.

Coradetti ST, et al. (2013 Aug). Analysis of a conserved cellulase transcriptional regulator reveals inducer-independent production of cellulolytic enzymes in Neurospora crassa.

Garzia A, et al. (2013 Feb). Transcriptional changes in the transition from vegetative cells to asexual development in the model fungus Aspergillus nidulans.

Brown NA, et al. (2013 Jun 25). Functional characterisation of the non-essential protein kinases and phosphatases regulating Aspergillus nidulans hydrolytic enzyme production.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG01734
EOG8N2Z6B

sce:absent

Genes: 5

AspGD Description
Putative endoglucanase IV|Ortholog(s) have cellulase activity and role in glucan catabolic process


References

Bok JW, et al. (2006 Jan). Genomic mining for Aspergillus natural products.

Bauer S, et al. (2006 Jul 25). Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

Coutinho PM, et al. (2009 Mar). Post-genomic insights into the plant polysaccharide degradation potential of Aspergillus nidulans and comparison to Aspergillus niger and Aspergillus oryzae.

Coradetti ST, et al. (2013 Aug). Analysis of a conserved cellulase transcriptional regulator reveals inducer-independent production of cellulolytic enzymes in Neurospora crassa.

Garzia A, et al. (2013 Feb). Transcriptional changes in the transition from vegetative cells to asexual development in the model fungus Aspergillus nidulans.

Brown NA, et al. (2013 Jun 25). Functional characterisation of the non-essential protein kinases and phosphatases regulating Aspergillus nidulans hydrolytic enzyme production.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG01735
EOG8N2Z6B

sce:absent

Genes: 3

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG01736
EOG8N2Z6B

sce:absent

Genes: 2

AspGD Description
Putative endo-glucanase|Ortholog(s) have cellulase activity and role in glucan catabolic process


References

Bok JW, et al. (2006 Jan). Genomic mining for Aspergillus natural products.

Bauer S, et al. (2006 Jul 25). Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

Coutinho PM, et al. (2009 Mar). Post-genomic insights into the plant polysaccharide degradation potential of Aspergillus nidulans and comparison to Aspergillus niger and Aspergillus oryzae.

Coradetti ST, et al. (2013 Aug). Analysis of a conserved cellulase transcriptional regulator reveals inducer-independent production of cellulolytic enzymes in Neurospora crassa.

Garzia A, et al. (2013 Feb). Transcriptional changes in the transition from vegetative cells to asexual development in the model fungus Aspergillus nidulans.

Brown NA, et al. (2013 Jun 25). Functional characterisation of the non-essential protein kinases and phosphatases regulating Aspergillus nidulans hydrolytic enzyme production.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG01737
EOG866T4K
EOG8W0VX9

sce:absent

Genes: 5

AspGD Description
Ortholog(s) have cellulase activity and role in glucan catabolic process|Putative endoglucanase IV


References

Bok JW, et al. (2006 Jan). Genomic mining for Aspergillus natural products.

Bauer S, et al. (2006 Jul 25). Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.

Coutinho PM, et al. (2009 Mar). Post-genomic insights into the plant polysaccharide degradation potential of Aspergillus nidulans and comparison to Aspergillus niger and Aspergillus oryzae.

Coradetti ST, et al. (2013 Aug). Analysis of a conserved cellulase transcriptional regulator reveals inducer-independent production of cellulolytic enzymes in Neurospora crassa.

Garzia A, et al. (2013 Feb). Transcriptional changes in the transition from vegetative cells to asexual development in the model fungus Aspergillus nidulans.

Brown NA, et al. (2013 Jun 25). Functional characterisation of the non-essential protein kinases and phosphatases regulating Aspergillus nidulans hydrolytic enzyme production.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG01738
EOG8CRJGJ
EOG8J9KF5
EOG8N2Z6B

sce:absent

Genes: 4

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 4 genes with posterior transmembrane prediction > 50%

FOG01739
EOG873NG9
EOG8CRJGJ

sce:absent

Genes: 3

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG01740
EOG83BK53

sce:absent

Genes: 2

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG01741
EOG83BK53
EOG8M6403

sce:absent

Genes: 2

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG01742
EOG873NG9

sce:absent

Genes: 1

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG01743
EOG8J9KF5

sce:absent

Genes: 2

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG01744
EOG866T4K

sce:absent

Genes: 1

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG01745
EOG8M6403

sce:absent

Genes: 2

PomBase Description
alpha-amylase homolog Aah4


AspGD Description
Putative alpha-glucanotransferase


References

Watanabe T, et al. (2001 Jun 1). Comprehensive isolation of meiosis-specific genes identifies novel proteins and unusual non-coding transcripts in Schizosaccharomyces pombe.

De Groot PW, et al. (2003 Jul 15). Genome-wide identification of fungal GPI proteins.

Morita T, et al. (2006 Jun). An alpha-amylase homologue, aah3, encodes a GPI-anchored membrane protein required for cell wall integrity and morphogenesis in Schizosaccharomyces pombe.

Amorim MJ, et al. (2010 Jun 8). Global coordination of transcriptional control and mRNA decay during cellular differentiation.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG01746
EOG8N2Z6B

sce:absent

Genes: 4

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%