FOG01693
EOG87D7XQ

sce:GSH1

Genes: 33

SGD Description
Gamma glutamylcysteine synthetase; catalyzes the first step in glutathione (GSH) biosynthesis; expression induced by oxidants, cadmium, and mercury; protein abundance increases in response to DNA replication stress


PomBase Description
glutamate-cysteine ligase Gcs1


AspGD Description
Ortholog(s) have glutamate-cysteine ligase activity, role in cellular response to cadmium ion, detoxification of cadmium ion, glutathione biosynthetic process, phytochelatin biosynthetic process and cytosol, nucleus localization


References

Ohtake Y, et al. (1991 Dec). Molecular cloning of the gamma-glutamylcysteine synthetase gene of Saccharomyces cerevisiae.

Lisowsky T, et al. (1993 May-Jun). A high copy number of yeast gamma-glutamylcysteine synthetase suppresses a nuclear mutation affecting mitochondrial translation.

Szilágyi M, et al. (2013 Jan). Transcriptome changes initiated by carbon starvation in Aspergillus nidulans.

Spitzmüller Z, et al. (2015 Jun). Degradation of glutathione in Aspergillus nidulans - Short communication.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 18 genes with posterior transmembrane prediction > 50%

FOG01694
EOG87D7XQ

sce:absent

Genes: 1

AspGD Description
Gamma-glutamylcysteine synthetase


References

Szilágyi M, et al. (2013 Jan). Transcriptome changes initiated by carbon starvation in Aspergillus nidulans.

Spitzmüller Z, et al. (2015 Jun). Degradation of glutathione in Aspergillus nidulans - Short communication.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%