FOG01642
EOG8JH9XW

sce:CAB1

Genes: 33

SGD Description
Pantothenate kinase, ATP:D-pantothenate 4'-phosphotransferase; catalyzes the first committed step in the universal biosynthetic pathway for synthesis of coenzyme A (CoA); transcriptionally regulated by Upc2p via a sterol response element


PomBase Description
fumble family pantothenate kinase (predicted)


AspGD Description
Pantothenate kinase


References

Kurtov D, et al. (1999 Aug). The Aspergillus nidulans panB gene encodes ketopantoate hydroxymethyltransferase, required for biosynthesis of pantothenate and Coenzyme A.

Calder RB, et al. (1999 Jan 22). Cloning and characterization of a eukaryotic pantothenate kinase gene (panK) from Aspergillus nidulans.

Rock CO, et al. (2000 Jan 14). Pantothenate kinase regulation of the intracellular concentration of coenzyme A.

Olzhausen J, et al. (2009 Apr). Genetic analysis of coenzyme A biosynthesis in the yeast Saccharomyces cerevisiae: identification of a conditional mutation in the pantothenate kinase gene CAB1.

Nakamura T, et al. (2012 Sep). Impaired coenzyme A synthesis in fission yeast causes defective mitosis, quiescence-exit failure, histone hypoacetylation and fragile DNA.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Beckley JR, et al. (2015 Dec). A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%