FOG01628
EOG844J3R

sce:NMA1;NMA2

Genes: 36

SGD Description
Nicotinic acid mononucleotide adenylyltransferase; catalyzes the transfer of the adenylyl moiety of ATP to nicotinamide mononucleotide to form NAD; involved in pathways of NAD biosynthesis, including the de novo, NAD(+) salvage, and nicotinamide riboside salvage pathways; homolog of human NMNAT; NMA1 has a paralog, NMA2, that arose from the whole genome duplication|Nicotinic acid mononucleotide adenylyltransferase; catalyzes the transfer of the adenylyl moiety of ATP to nicotinamide mononucleotide to form NAD; involved in de novo and salvage synthesis of NAD(+); homolog of human NMNAT; NMA2 has a paralog, NMA1, that arose from the whole genome duplication


PomBase Description
nicotinamide mononucleotide (NMN) adenylyltransferase (predicted)


AspGD Description
Nicotinamide-nucleotide adenylyltransferase


References

KORNBERG A, et al. (1948 Dec). The participation of inorganic pyrophosphate in the reversible enzymatic synthesis of diphosphopyridine nucleotide.

Dahmen W, et al. (1967 May). The deamido-diphosphopyridine nucleotide and diphosphopyridine nucleotide pyrophosphorylases of Escherichia coli and yeast.

Natalini P, et al. (1986 Jun 17). Nicotinamide mononucleotide adenylyltransferase. Molecular and enzymatic properties of the homogeneous enzyme from baker's yeast.

Emanuelli M, et al. (1999 Jul 16). Identification and characterization of YLR328W, the Saccharomyces cerevisiae structural gene encoding NMN adenylyltransferase. Expression and characterization of the recombinant enzyme.

Anderson RM, et al. (2002 May 24). Manipulation of a nuclear NAD+ salvage pathway delays aging without altering steady-state NAD+ levels.

Emanuelli M, et al. (2003 Feb). Identification and characterization of a second NMN adenylyltransferase gene in Saccharomyces cerevisiae.

Chikashige Y, et al. (2006 Apr 7). Meiotic proteins bqt1 and bqt2 tether telomeres to form the bouquet arrangement of chromosomes.

Wilson-Grady JT, et al. (2008 Mar). Phosphoproteome analysis of fission yeast.

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Rhind N, et al. (2011 May 20). Comparative functional genomics of the fission yeasts.

Das J, et al. (2013 May 21). Cross-species protein interactome mapping reveals species-specific wiring of stress response pathways.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Kato M, et al. (2014 May 30). YCL047C/POF1 is a novel nicotinamide mononucleotide adenylyltransferase (NMNAT) in Saccharomyces cerevisiae.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 20 genes with posterior transmembrane prediction > 50%