FOG01590
EOG8TX9C6

sce:HNT1

Genes: 30

SGD Description
Adenosine 5'-monophosphoramidase; interacts physically and genetically with Kin28p, a CDK and TFIIK subunit, and genetically with CAK1; member of the histidine triad (HIT) superfamily of nucleotide-binding proteins and similar to Hint; protein abundance increases in response to DNA replication stress


PomBase Description
adenosine 5'-monophosphoramidase (predicted)


AspGD Description
Putative HIT family protein; repressed by growth on starch and lactate


References

Fröhlich KU, et al. (1991 Aug). Yeast cell cycle protein CDC48p shows full-length homology to the mammalian protein VCP and is a member of a protein family involved in secretion, peroxisome formation, and gene expression.

Séraphin B, et al. (1992). The HIT protein family: a new family of proteins present in prokaryotes, yeast and mammals.

Korsisaari N, et al. (2000 Nov 10). Interactions of Cdk7 and Kin28 with Hint/PKCI-1 and Hnt1 histidine triad proteins.

Bieganowski P, et al. (2002 Mar 29). Adenosine monophosphoramidase activity of Hint and Hnt1 supports function of Kin28, Ccl1, and Tfb3.

Muthuvijayan V, et al. (2004). In silico reconstruction of nutrient-sensing signal transduction pathways in Aspergillus nidulans.

Gaisne M, et al. (2006 Sep). The COX18 gene, involved in mitochondrial biogenesis, is functionally conserved and tightly regulated in humans and fission yeast.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Caetano JS, et al. (2014 Jan). Autosomal recessive axonal neuropathy with neuromyotonia: a rare entity.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG01591
EOG8TX9C6

sce:absent

Genes: 7

AspGD Description
Has domain(s) with predicted catalytic activity

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 4 genes with posterior transmembrane prediction > 50%