FOG01561
EOG84F4SV

sce:URA1

Genes: 8

SGD Description
Dihydroorotate dehydrogenase; catalyzes the fourth enzymatic step in the de novo biosynthesis of pyrimidines, converting dihydroorotic acid into orotic acid


References

Nagy M, et al. (1992 Oct 1). Divergent evolution of pyrimidine biosynthesis between anaerobic and aerobic yeasts.

Roy A, et al. (1992 Sep 1). Nucleotide sequence of the URA1 gene of Saccharomyces cerevisiae.

Jordan DB, et al. (2000 Jun 1). Catalytic properties of dihydroorotate dehydrogenase from Saccharomyces cerevisiae: studies on pH, alternate substrates, and inhibitors.

Leh-Louis V, et al. (2004). Differential evolution of the Saccharomyces cerevisiae DUP240 paralogs and implication of recombination in phylogeny.

Zameitat E, et al. (2004 Jun 18). Two different dihydroorotate dehydrogenases from yeast Saccharomyces kluyveri.

Gojković Z, et al. (2004 May). Horizontal gene transfer promoted evolution of the ability to propagate under anaerobic conditions in yeasts.

Hall C, et al. (2005 Jun). Contribution of horizontal gene transfer to the evolution of Saccharomyces cerevisiae.

Zameitat E, et al. (2007 Sep). Dihydroorotate dehydrogenase from Saccharomyces cerevisiae: spectroscopic investigations with the recombinant enzyme throw light on catalytic properties and metabolism of fumarate analogues.

Starita LM, et al. (2012 Jan). Sites of ubiquitin attachment in Saccharomyces cerevisiae.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%