FOG01541
EOG825485

sce:YND1

Genes: 33

SGD Description
Apyrase with wide substrate specificity; helps prevent inhibition of glycosylation by hydrolyzing nucleoside tri- and diphosphates that inhibit glycotransferases; partially redundant with Gda1p; mediates adenovirus E4orf4-induced toxicity


PomBase Description
nucleoside diphosphatase Ynd1


AspGD Description
Putative apyrase, nucleoside diphosphatase; induced by fenpropimorph


References

Gao XD, et al. (1999 Jul 23). YND1, a homologue of GDA1, encodes membrane-bound apyrase required for Golgi N- and O-glycosylation in Saccharomyces cerevisiae.

Zhong X, et al. (2000 Nov 10). Regulation of yeast ectoapyrase ynd1p activity by activator subunit Vma13p of vacuolar H+-ATPase.

Maoz T, et al. (2005 Dec 16). YND1 interacts with CDC55 and is a novel mediator of E4orf4-induced toxicity.

Valachovic M, et al. (2006 Aug). Cumulative mutations affecting sterol biosynthesis in the yeast Saccharomyces cerevisiae result in synthetic lethality that is suppressed by alterations in sphingolipid profiles.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 27 genes with posterior transmembrane prediction > 50%

FOG01542
EOG825485

sce:GDA1

Genes: 34

SGD Description
Guanosine diphosphatase located in the Golgi; involved in the transport of GDP-mannose into the Golgi lumen by converting GDP to GMP after mannose is transferred its substrate


PomBase Description
guanosine-diphosphatase Gda1


AspGD Description
Putative guanosine diphosphatase; expression enhanced by maltose


References

Abeijon C, et al. (1993 Jul). Guanosine diphosphatase is required for protein and sphingolipid glycosylation in the Golgi lumen of Saccharomyces cerevisiae.

Berninsone P, et al. (1995 Jun 16). Regulation of yeast Golgi glycosylation. Guanosine diphosphatase functions as a homodimer in the membrane.

Lopez-Avalos MD, et al. (2001 May). The UDPase activity of the Kluyveromyces lactis Golgi GDPase has a role in uridine nucleotide sugar transport into Golgi vesicles.

Herrero AB, et al. (2002 Jun). The Golgi GDPase of the fungal pathogen Candida albicans affects morphogenesis, glycosylation, and cell wall properties.

D'Alessio C, et al. (2003 Jun 20). Nucleoside diphosphatase and glycosyltransferase activities can localize to different subcellular compartments in Schizosaccharomyces pombe.

Sánchez R, et al. (2003 Nov 7). Characterization of gdp1+ as encoding a GDPase in the fission yeast Schizosaccharomyces pombe.

Das J, et al. (2013 May 21). Cross-species protein interactome mapping reveals species-specific wiring of stress response pathways.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 11 genes with posterior transmembrane prediction > 50%

FOG01543
EOG825485

sce:absent

Genes: 18

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 16 genes with posterior transmembrane prediction > 50%

FOG01544
EOG825485

sce:absent

Genes: 2

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG01545
EOG825485

sce:absent

Genes: 1

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%