FOG01532
EOG8SF7RD

sce:APT1

Genes: 34

SGD Description
Adenine phosphoribosyltransferase; catalyzes the formation of AMP from adenine and 5-phosphoribosylpyrophosphate; involved in the salvage pathway of purine nucleotide biosynthesis; APT1 has a paralog, APT2, that arose from the whole genome duplication


PomBase Description
adenine phosphoribosyltransferase (APRT) (predicted)


AspGD Description
Adenine phosphoribosyltransferase with a predicted role in adenine salvage pathway


References

Housset P, et al. (1977 Feb 15). Study of the role of puring phosphoribosyltransferases in the uptake of adenine and guanine by Schizosaccharomyces pombe cells.

Nagy M, et al. (1977 Jul 1). Purification and comparative study of adenine and guanine phosphoribosyltransferases from Schizosaccharomyces pombe.

Alfonzo JD, et al. (1995 Aug 8). Cloning and characterization of the adenine phosphoribosyltransferase-encoding gene (APT1) from Saccharomyces cerevisiae.

Alfonzo JD, et al. (1997 Sep 5). Purification and characterization of adenine phosphoribosyltransferase from Saccharomyces cerevisiae.

Alfonzo JD, et al. (1999 Jan). APT1, but not APT2, codes for a functional adenine phosphoribosyltransferase in Saccharomyces cerevisiae.

Shi W, et al. (2001 Sep 11). Structural analysis of adenine phosphoribosyltransferase from Saccharomyces cerevisiae.

Chen D, et al. (2003 Jan). Global transcriptional responses of fission yeast to environmental stress.

Hogan CJ, et al. (2010 Feb). Fission yeast Iec1-ino80-mediated nucleosome eviction regulates nucleotide and phosphate metabolism.

Takeda K, et al. (2011). Identification of genes affecting the toxicity of anti-cancer drug bortezomib by genome-wide screening in S. pombe.

Stewart EV, et al. (2011 Apr 22). Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.

Pusztahelyi T, et al. (2011 Feb). Comparison of transcriptional and translational changes caused by long-term menadione exposure in Aspergillus nidulans.

Anver S, et al. (2014 Aug). Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Beckley JR, et al. (2015 Dec). A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 9 genes with posterior transmembrane prediction > 50%

FOG01533
EOG8SF7RD

sce:APT2

Genes: 1

SGD Description
Potential adenine phosphoribosyltransferase; encodes a protein with similarity to adenine phosphoribosyltransferase, but artificially expressed protein exhibits no enzymatic activity; APT2 has a paralog, APT1, that arose from the whole genome duplication


References

Yuryev A, et al. (1994 May). A Saccharomyces cerevisiae gene encoding a potential adenine phosphoribosyltransferase.

Alfonzo JD, et al. (1999 Jan). APT1, but not APT2, codes for a functional adenine phosphoribosyltransferase in Saccharomyces cerevisiae.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%