FOG01525
EOG8S7H6F

sce:AAH1

Genes: 25

SGD Description
Adenine deaminase (adenine aminohydrolase); converts adenine to hypoxanthine; involved in purine salvage; transcriptionally regulated by nutrient levels and growth phase; Aah1p degraded upon entry into quiescence via SCF and the proteasome


PomBase Description
adenine deaminase Dea2


AspGD Description
Adenosine deaminase


References

Scazzocchio C, et al. (1982 Feb). Positive regulation in a eukaryote, a study of the uaY gene of Aspergillus nidulans: I. Characterization of alleles, dominance and complementation studies, and a fine structure map of the uaY--oxpA cluster.

Suárez T, et al. (1991 Dec). The uaY positive control gene of Aspergillus nidulans: fine structure, isolation of constitutive mutants and reversion patterns.

Deeley MC, et al. (1992 May). Adenine deaminase and adenine utilization in Saccharomyces cerevisiae.

Scazzocchio C, et al. (1994). The purine degradation pathway, genetics, biochemistry and regulation.

Ribard C, et al. (2001 Dec). The oxpA5 mutation of Aspergillus nidulans is an allele of adB, the gene encoding adenylosuccinate synthetase.

Ribard C, et al. (2003 Dec 12). Sub-families of alpha/beta barrel enzymes: a new adenine deaminase family.

Escusa S, et al. (2007 Jul 13). Skp1-Cullin-F-box-dependent degradation of Aah1p requires its interaction with the F-box protein Saf1p.

Pospísilová H, et al. (2008 Dec). Hydrolytic cleavage of N6-substituted adenine derivatives by eukaryotic adenine and adenosine deaminases.

Oestreicher N, et al. (2008 May). The nadA gene of Aspergillus nidulans, encoding adenine deaminase, is subject to a unique regulatory pattern.

Robellet X, et al. (2010 Aug). Gene silencing of transgenes inserted in the Aspergillus nidulans alcM and/or alcS loci.

Macios M, et al. (2012 Mar). The GATA factors AREA and AREB together with the co-repressor NMRA, negatively regulate arginine catabolism in Aspergillus nidulans in response to nitrogen and carbon source.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG01526
EOG8S7H6F

sce:absent

Genes: 6

PomBase Description
adenine deaminase (predicted)


AspGD Description
Adenosine deaminase


References

Ribard C, et al. (2003 Dec 12). Sub-families of alpha/beta barrel enzymes: a new adenine deaminase family.

Stewart EV, et al. (2011 Apr 22). Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.

Anver S, et al. (2014 Aug). Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts.

Dudin O, et al. (2017 Apr). A systematic screen for morphological abnormalities during fission yeast sexual reproduction identifies a mechanism of actin aster formation for cell fusion.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%