FOG01416
EOG83TXBQ

sce:YHB1

Genes: 31

SGD Description
Nitric oxide oxidoreductase; flavohemoglobin involved in nitric oxide detoxification; plays a role in the oxidative and nitrosative stress responses; protein increases in abundance and relocalizes from nucleus to cytoplasmic foci upon DNA replication stress


PomBase Description
nitric oxide dioxygenase (predicted)


AspGD Description
Flavohemoglobin|Has domain(s) with predicted heme binding, iron ion binding, oxygen binding activity and role in oxygen transport


References

Zhu H, et al. (1992 Jun 1). Yeast flavohemoglobin is an ancient protein related to globins and a reductase family.

Crawford MJ, et al. (1995 Mar 24). Regulation of Saccharomyces cerevisiae flavohemoglobin gene expression.

Zhao XJ, et al. (1996 Oct 11). Function and expression of flavohemoglobin in Saccharomyces cerevisiae. Evidence for a role in the oxidative stress response.

Buisson N, et al. (1998 Apr 17). Flavohemoglobin expression and function in Saccharomyces cerevisiae. No relationship with respiration and complex response to oxidative stress.

Liu L, et al. (2000 Apr 25). Protection from nitrosative stress by yeast flavohemoglobin.

Gardner PR, et al. (2000 Oct 13). Nitric-oxide dioxygenase activity and function of flavohemoglobins. sensitivity to nitric oxide and carbon monoxide inhibition.

Nantel A, et al. (2002 Oct). Transcription profiling of Candida albicans cells undergoing the yeast-to-hyphal transition.

Chen D, et al. (2003 Jan). Global transcriptional responses of fission yeast to environmental stress.

Ullmann BD, et al. (2004 Jun). Inducible defense mechanism against nitric oxide in Candida albicans.

Lorenz MC, et al. (2004 Oct). Transcriptional response of Candida albicans upon internalization by macrophages.

Lan CY, et al. (2004 Sep). Regulatory networks affected by iron availability in Candida albicans.

Helmick RA, et al. (2005 May). Imidazole antibiotics inhibit the nitric oxide dioxygenase function of microbial flavohemoglobin.

Hromatka BS, et al. (2005 Oct). Transcriptional response of Candida albicans to nitric oxide and the role of the YHB1 gene in nitrosative stress and virulence.

Zakikhany K, et al. (2007 Dec). In vivo transcript profiling of Candida albicans identifies a gene essential for interepithelial dissemination.

Chiranand W, et al. (2008 Feb). CTA4 transcription factor mediates induction of nitrosative stress response in Candida albicans.

Marcil A, et al. (2008 Sep). Analysis of PRA1 and its relationship to Candida albicans- macrophage interactions.

Shimizu M, et al. (2009 Jan). Proteomic analysis of Aspergillus nidulans cultured under hypoxic conditions.

Sato I, et al. (2009 Mar 20). The glutathione system of Aspergillus nidulans involves a fungus-specific glutathione S-transferase.

Arana DM, et al. (2010 Jan). Fluconazole at subinhibitory concentrations induces the oxidative- and nitrosative-responsive genes TRR1, GRE2 and YHB1, and enhances the resistance of Candida albicans to phagocytes.

Schinko T, et al. (2010 Nov). Transcriptome analysis of nitrate assimilation in Aspergillus nidulans reveals connections to nitric oxide metabolism.

Baidya S, et al. (2011 Aug). Role of nitric oxide and flavohemoglobin homolog genes in Aspergillus nidulans sexual development and mycotoxin production.

Hsu PC, et al. (2011 Feb). Candida albicans Hap43 is a repressor induced under low-iron conditions and is essential for iron-responsive transcriptional regulation and virulence.

Pusztahelyi T, et al. (2011 Feb). Comparison of transcriptional and translational changes caused by long-term menadione exposure in Aspergillus nidulans.

Freitas JS, et al. (2011 Sep). Transcription of the Hsp30, Hsp70, and Hsp90 heat shock protein genes is modulated by the PalA protein in response to acid pH-sensing in the fungus Aspergillus nidulans.

Lando D, et al. (2012). The S. pombe histone H2A dioxygenase Ofd2 regulates gene expression during hypoxia.

Miramón P, et al. (2012). Cellular responses of Candida albicans to phagocytosis and the extracellular activities of neutrophils are critical to counteract carbohydrate starvation, oxidative and nitrosative stress.

Sellam A, et al. (2012). A novel role for the transcription factor Cwt1p as a negative regulator of nitrosative stress in Candida albicans.

Dyer PS, et al. (2012 Jan). Sexual development and cryptic sexuality in fungi: insights from Aspergillus species.

Zhou S, et al. (2012 Jan). Heme-biosynthetic porphobilinogen deaminase protects Aspergillus nidulans from nitrosative stress.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Schinko T, et al. (2013 May). Pseudo-constitutivity of nitrate-responsive genes in nitrate reductase mutants.

Sun X, et al. (2013 May). PyrG is required for maintaining stable cellular uracil level and normal sporulation pattern under excess uracil stress in Aspergillus nidulans.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Marcos AT, et al. (2016 Jan). Nitric oxide synthesis by nitrate reductase is regulated during development in Aspergillus.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
10 genes with posterior transmembrane prediction > 50%


FOG01417
EOG83TXBQ

sce:absent

Genes: 1
 





 
Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50%