FOG01412
EOG8905TF
EOG8JH9ZK

sce:AIM17

Genes: 26

SGD Description
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays reduced frequency of mitochondrial genome loss


AspGD Description
Ortholog(s) have gamma-butyrobetaine dioxygenase activity and role in carnitine biosynthetic process


References

Atcheson CL, et al. (1987 Nov). Isolation, DNA sequence, and regulation of a meiosis-specific eukaryotic recombination gene.

Reinders J, et al. (2006 Jul). Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

Malavazi I, et al. (2007 Oct). Transcriptome analysis of the Aspergillus nidulans AtmA (ATM, Ataxia-Telangiectasia mutated) null mutant.

Hess DC, et al. (2009 Mar). Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis.

Bayot A, et al. (2010 Apr 9). Identification of novel oxidized protein substrates and physiological partners of the mitochondrial ATP-dependent Lon-like protease Pim1.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG01413
EOG8JH9ZK
COX10
sce:COX10

Genes: 33

SGD Description
Heme A:farnesyltransferase; catalyzes the first step in the conversion of protoheme to the heme A prosthetic group required for cytochrome c oxidase activity; human ortholog is associated with mitochondrial disorders


PomBase Description
protoheme IX farnesyltransferase (predicted)


AspGD Description
Ortholog(s) have role in heme a biosynthetic process and mitochondrion localization


References

Nobrega MP, et al. (1990 Aug 25). COX10 codes for a protein homologous to the ORF1 product of Paracoccus denitrificans and is required for the synthesis of yeast cytochrome oxidase.

Tzagoloff A, et al. (1993 Nov). On the functions of the yeast COX10 and COX11 gene products.

Niino YS, et al. (1995 Feb 3). A new old yellow enzyme of Saccharomyces cerevisiae.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 33 genes with posterior transmembrane prediction > 50%