FOG01371
EOG8K0P47

sce:MET2

Genes: 34

SGD Description
L-homoserine-O-acetyltransferase; catalyzes the conversion of homoserine to O-acetyl homoserine which is the first step of the methionine biosynthetic pathway


PomBase Description
homoserine O-acetyltransferase Met6


AspGD Description
Homoserine O-acetyltransferase


References

Bal J, et al. (1979 Dec). Allele specific and locus non-specific suppressors in Aspergillus nidulans.

Langin T, et al. (1986). The MET2 gene of Saccharomyces cerevisiae: molecular cloning and nucleotide sequence.

Paszewski A, et al. (1994). Sulphur metabolism.

Schweingruber AM, et al. (1998 Dec). Methionine induces sexual development in the fission yeast Schizosaccharomyces pombe via an ste11-dependent signalling pathway.

Grynberg M, et al. (2001 May 28). The Aspergillus nidulans metE gene is regulated by a second system independent from sulphur metabolite repression.

Kumar A, et al. (2002 Mar 15). Subcellular localization of the yeast proteome.

Han YK, et al. (2004 Oct). Functional analysis of the homoserine O-acetyltransferase gene and its identification as a selectable marker in Gibberella zeae.

Fujita Y, et al. (2006 Feb). Homocysteine accumulation causes a defect in purine biosynthesis: further characterization of Schizosaccharomyces pombe methionine auxotrophs.

Ma Y, et al. (2007 Aug). Six new amino acid-auxotrophic markers for targeted gene integration and disruption in fission yeast.

Deshpande GP, et al. (2009 May 1). Screening a genome-wide S. pombe deletion library identifies novel genes and pathways involved in genome stability maintenance.

Takeda K, et al. (2011). Identification of genes affecting the toxicity of anti-cancer drug bortezomib by genome-wide screening in S. pombe.

Rhind N, et al. (2011 May 20). Comparative functional genomics of the fission yeasts.

García-Santamarina S, et al. (2013 Dec). Methionine sulphoxide reductases revisited: free methionine as a primary target of H₂O₂stress in auxotrophic fission yeast.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Burr R, et al. (2016 Jun 3). Mga2 Transcription Factor Regulates an Oxygen-responsive Lipid Homeostasis Pathway in Fission Yeast.

Malecki M, et al. (2016 Nov 25). Functional and regulatory profiling of energy metabolism in fission yeast.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 4 genes with posterior transmembrane prediction > 50%