FOG01340
EOG88933C

sce:BNA2

Genes: 28

SGD Description
Tryptophan 2,3-dioxygenase or indoleamine 2,3-dioxygenase; required for de novo biosynthesis of NAD from tryptophan via kynurenine; interacts genetically with telomere capping gene CDC13; regulated by Hst1p and Aftp


AspGD Description
Putative indoleamine 2,3-dioxygenase


References

Panozzo C, et al. (2002 Apr 24). Aerobic and anaerobic NAD+ metabolism in Saccharomyces cerevisiae.

Rutherford JC, et al. (2003 Jul 25). Aft1p and Aft2p mediate iron-responsive gene expression in yeast through related promoter elements.

Bedalov A, et al. (2003 Oct). NAD+-dependent deacetylase Hst1p controls biosynthesis and cellular NAD+ levels in Saccharomyces cerevisiae.

Greenall A, et al. (2008 Oct 1). A genome wide analysis of the response to uncapped telomeres in budding yeast reveals a novel role for the NAD+ biosynthetic gene BNA2 in chromosome end protection.

Yuasa HJ, et al. (2011 Feb). Molecular evolution and characterization of fungal indoleamine 2,3-dioxygenases.

Colabardini AC, et al. (2013). Functional characterization of Aspergillus nidulans ypkA, a homologue of the mammalian kinase SGK.

Rodríguez-Colman MJ, et al. (2013 Aug). The FOX transcription factor Hcm1 regulates oxidative metabolism in response to early nutrient limitation in yeast. Role of Snf1 and Tor1/Sch9 kinases.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 3 genes with posterior transmembrane prediction > 50%

FOG01341
EOG88933C

sce:absent

Genes: 2

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG01342
EOG88933C

sce:absent

Genes: 3

AspGD Description
Ortholog(s) have indoleamine 2,3-dioxygenase activity

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%