FOG01310
EOG8Q575V

sce:ARO4

Genes: 33

SGD Description
3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase; catalyzes the first step in aromatic amino acid biosynthesis and is feedback-inhibited by tyrosine or high concentrations of phenylalanine or tryptophan; relative distribution to the nucleus increases upon DNA replication stress


PomBase Description
phospho-2-dehydro-3-deoxyheptonate aldolase (predicted)


AspGD Description
Ortholog(s) have 3-deoxy-7-phosphoheptulonate synthase activity and role in aromatic amino acid family biosynthetic process


References

Künzler M, et al. (1992 Apr 1). Cloning, primary structure and regulation of the ARO4 gene, encoding the tyrosine-inhibited 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Saccharomyces cerevisiae.

Kuenzler M, et al. (1993 Sep). Cloning, primary structure, and regulation of the HIS7 gene encoding a bifunctional glutamine amidotransferase: cyclase from Saccharomyces cerevisiae.

Pereira SA, et al. (1996 Apr). Aromatic amino-acid biosynthesis in Candida albicans: identification of the ARO4 gene encoding a second DAHP synthase.

Hartmann M, et al. (2001 Feb). Regulative fine-tuning of the two novel DAHP isoenzymes aroFp and aroGp of the filamentous fungus Aspergillus nidulans.

Hartmann M, et al. (2003 Feb 4). Evolution of feedback-inhibited beta /alpha barrel isoenzymes by gene duplication and a single mutation.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG01311
EOG8Q575V

sce:ARO3

Genes: 32

SGD Description
3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase; catalyzes the first step in aromatic amino acid biosynthesis and is feedback-inhibited by phenylalanine or high concentration of tyrosine or tryptophan


PomBase Description
phospho-2-dehydro-3-deoxyheptonate aldolase (predicted)


AspGD Description
3-deoxy-7-phosphoheptulonate synthase


References

Paravicini G, et al. (1988 Sep). Structure of the ARO3 gene of Saccharomyces cerevisiae.

Hartmann M, et al. (2001 Feb). Regulative fine-tuning of the two novel DAHP isoenzymes aroFp and aroGp of the filamentous fungus Aspergillus nidulans.

Woodard RW, et al. (2004 Oct). Unique biosynthesis of dehydroquinic acid?

Hortschansky P, et al. (2007 Jul 11). Interaction of HapX with the CCAAT-binding complex--a novel mechanism of gene regulation by iron.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%