FOG00976
EOG8ZW3SX
UGA1
sce:UGA1

Genes: 34

Protein description
Cytoplasmic gamma-aminobutyrate (GABA) transaminase


Features
[c]


SGD Description
Gamma-aminobutyrate (GABA) transaminase; also known as 4-aminobutyrate aminotransferase; involved in the 4-aminobutyrate and glutamate degradation pathways; required for normal oxidative stress tolerance and nitrogen utilization; protein abundance increases in response to DNA replication stress


PomBase Description
4-aminobutyrate aminotransferase (GABA transaminase)


AspGD Description
Gamma-aminobutyrate transaminase


References

Arst HN Jr, et al. (1976 Jul 15). Integrator gene in Aspergillus nidulans.

Hynes MJ, et al. (1978 Apr 25). Multiple independent control mechanisms affecting the acetamidase of Aspergillus nidulans.

Arst HN Jr, et al. (1978 Jul 6). GABA transaminase provides an alternative route of beta-alanine synthesis in Aspergillus nidulans.

Arst HN Jr, et al. (1980 Mar). A possible rôle for acid phosphatase in gamma-amino-n-butyrate uptake in Aspergillus nidulans.

Bailey CR, et al. (1980 Oct). A third gene affecting GABA transaminase levels in Aspergillus nidulans.

Arst HN Jr, et al. (1984 Sep). Regulation of gene expression in Aspergillus nidulans.

Ramos F, et al. (1985 Jun 3). Mutations affecting the enzymes involved in the utilization of 4-aminobutyric acid as nitrogen source by the yeast Saccharomyces cerevisiae.

Hynes MJ, et al. (1986 Sep). The amdS gene of Aspergillus nidulans: control by multiple regulatory signals.

Andrianopoulos A, et al. (1988 Aug). Cloning and analysis of the positively acting regulatory gene amdR from Aspergillus nidulans.

Katz ME, et al. (1989 Jun). Characterization of the amdR-controlled lamA and lamB genes of Aspergillus nidulans.

Richardson IB, et al. (1989 May). Cloning and molecular characterisation of the amdR controlled gatA gene of Aspergillus nidulans.

André B, et al. (1990 May 25). Nucleotide sequence of the yeast UGA1 gene encoding GABA transaminase.

Lloyd AT, et al. (1991 Nov). Codon usage in Aspergillus nidulans.

Richardson IB, et al. (1992 Jan). Molecular characterization of the lam locus and sequences involved in regulation by the AmdR protein of Aspergillus nidulans.

Davis MA, et al. (1993). Fungal catabolic gene regulation: molecular genetic analysis of the amdS gene of Aspergillus nidulans.

Hynes MJ, et al. (1994). Regulation of acetamide utilization.

Chang PK, et al. (1996 Jun). Characterization of the Aspergillus parasiticus niaD and niiA gene cluster.

Straffon MJ, et al. (1996 Mar). Characterization of the ugatA gene of Ustilago maydis, isolated by homology to the gatA gene of Aspergillus nidulans.

Clutterbuck AJ, et al. (1997 Jun). The validity of the Aspergillus nidulans linkage map.

Kato M, et al. (1997 Mar 26). An Aspergillus nidulans nuclear protein, AnCP, involved in enhancement of Taka-amylase A gene expression, binds to the CCAAT-containing taaG2, amdS, and gatA promoters.

Chang PK, et al. (2000 Apr 25). Characterization of the Aspergillus parasiticus major nitrogen regulatory gene, areA.

Kumar A, et al. (2002 Mar 15). Subcellular localization of the yeast proteome.

Andersen G, et al. (2007 Apr). A gene duplication led to specialized gamma-aminobutyrate and beta-alanine aminotransferase in yeast.

Schnackerz KD, et al. (2008 Jun). Degradation of pyrimidines in Saccharomyces kluyveri: transamination of beta-alanine.

Shimizu M, et al. (2009 Jan). Proteomic analysis of Aspergillus nidulans cultured under hypoxic conditions.

Bach B, et al. (2009 Jul). New insights into {gamma}-aminobutyric acid catabolism: Evidence for {gamma}-hydroxybutyric acid and polyhydroxybutyrate synthesis in Saccharomyces cerevisiae.

Masuo S, et al. (2010 Dec). Global gene expression analysis of Aspergillus nidulans reveals metabolic shift and transcription suppression under hypoxia.

Gerke J, et al. (2012 Jun). Fungal S-adenosylmethionine synthetase and the control of development and secondary metabolism in Aspergillus nidulans.

Cao J, et al. (2013 Apr). GABA shunt mediates thermotolerance in Saccharomyces cerevisiae by reducing reactive oxygen production.

Lee JY, et al. (2013 Dec). A putative APSES transcription factor is necessary for normal growth and development of Aspergillus nidulans.

Cao J, et al. (2013 Jul). GABA transaminases from Saccharomyces cerevisiae and Arabidopsis thaliana complement function in cytosol and mitochondria.

Tudzynski B, et al. (2014). Nitrogen regulation of fungal secondary metabolism in fungi.

Schumacher J, et al. (2014 Jan). The transcription factor BcLTF1 regulates virulence and light responses in the necrotrophic plant pathogen Botrytis cinerea.

Romagnoli G, et al. (2014 Jul). An alternative, arginase-independent pathway for arginine metabolism in Kluyveromyces lactis involves guanidinobutyrase as a key enzyme.

Downes DJ, et al. (2014 Jun). Dual DNA binding and coactivator functions of Aspergillus nidulans TamA, a Zn(II)2Cys6 transcription factor.

Lee MK, et al. (2014 May). NsdD is a key repressor of asexual development in Aspergillus nidulans.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG00977
EOG8ZW3SX
UGA1.2
sce:absent

Genes: 13

Protein description
Mitochondrial gamma-aminobutyrate (GABA) transaminase


Features
[m]


Parent
paralog:FOG00976

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%