FOG00970
EOG8N02WM
MSL0
sce:absent
Genes: 6
Protein descriptionMalate synthase, located in glyoxysome in fungi. Sequences have SKL; fungal gene have introns,
Features[x];[c]?
AspGD DescriptionMalate synthase
References
Armitt S, et al. (1971 Jan 30). Mutants of Aspergillus nidulans lacking malate synthase.
Armitt S, et al. (1976 Feb). Analysis of acetate non-utilizing (acu) mutants in Aspergillus nidulans.
Payton M, et al. (1976 May). Agar as a carbon source and its effect on the utilization of other carbon sources by acetate non-utilizing (acu) mutants of Aspergillus nidulans.
Hynes MJ, et al. (1986 Sep). The amdS gene of Aspergillus nidulans: control by multiple regulatory signals.
Thomas GH, et al. (1988 Sep). Molecular cloning, identification and transcriptional analysis of genes involved in acetate utilization in Neurospora crassa.
Sandeman RA, et al. (1989 Jul). Isolation of the facA (acetyl-coenzyme A synthetase) and acuE (malate synthase) genes of Aspergillus nidulans.
Sandeman RA, et al. (1991 Sep). Molecular organisation of the malate synthase genes of Aspergillus nidulans and Neurospora crassa.
Hartig A, et al. (1992 Nov 11). Differentially regulated malate synthase genes participate in carbon and nitrogen metabolism of S. cerevisiae.
Kawasaki L, et al. (1995 Mar). Aspergillus nidulans mutants affected in acetate metabolism isolated as lipid nonutilizers.
De Lucas JR, et al. (1997 Dec). Characterization of oleate-nonutilizing mutants of Aspergillus nidulans isolated by the 3-amino-1,2,4-triazole positive selection method.
Clutterbuck AJ, et al. (1997 Jun). The validity of the Aspergillus nidulans linkage map.
Todd RB, et al. (1998 Apr 1). FacB, the Aspergillus nidulans activator of acetate utilization genes, binds dissimilar DNA sequences.
Stemple CJ, et al. (1998 Dec). The facC gene of Aspergillus nidulans encodes an acetate-inducible carnitine acetyltransferase.
Valenciano S, et al. (1998 Oct). Characterization of Aspergillus nidulans peroxisomes by immunoelectron microscopy.
Sims AH, et al. (2004 Feb). Use of expressed sequence tag analysis and cDNA microarrays of the filamentous fungus Aspergillus nidulans.
David H, et al. (2006). Metabolic network driven analysis of genome-wide transcription data from Aspergillus nidulans.
Hynes MJ, et al. (2006 May). Regulatory genes controlling fatty acid catabolism and peroxisomal functions in the filamentous fungus Aspergillus nidulans.
Hynes MJ, et al. (2008 Mar). Genetic analysis of the role of peroxisomes in the utilization of acetate and fatty acids in Aspergillus nidulans.
Flipphi M, et al. (2009 Mar). Biodiversity and evolution of primary carbon metabolism in Aspergillus nidulans and other Aspergillus spp.
Zekert N, et al. (2010 May). Interaction of the Aspergillus nidulans microtubule-organizing center (MTOC) component ApsB with gamma-tubulin and evidence for a role of a subclass of peroxisomes in the formation of septal MTOCs.
Flipphi M, et al. (2014 Jul). The Aspergillus nidulans acuL gene encodes a mitochondrial carrier required for the utilization of carbon sources that are metabolized via the TCA cycle.
FOG00971
EOG8N02WM
MLS1.2
sce:absent
Genes: 14
Protein descriptionPeroxisomal malate synthase
Features[x]
Parentortholog:FOG00970
FOG00972
EOG8N02WM
MSL1
sce:MLS1
Genes: 21
Protein descriptionCytoplasmic malate synthase, non-fermentable carbon sources; cytosolic but sce ortholog can localize in [x] when grown on oleate
Features[c]
Parentparalog:FOG00970
SGD DescriptionMalate synthase, enzyme of the glyoxylate cycle; involved in utilization of non-fermentable carbon sources; expression is subject to carbon catabolite repression; localizes in peroxisomes during growth on oleic acid, otherwise cytosolic; can accept butyryl-CoA as acyl-CoA donor in addition to traditional substrate acetyl-CoA
References
Hartig A, et al. (1992 Nov 11). Differentially regulated malate synthase genes participate in carbon and nitrogen metabolism of S. cerevisiae.
Fay JC, et al. (2005 Jul). Evidence for domesticated and wild populations of Saccharomyces cerevisiae.
Sinha H, et al. (2008 Nov). Sequential elimination of major-effect contributors identifies additional quantitative trait loci conditioning high-temperature growth in yeast.
Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.
FOG00973
EOG8N02WM
DAL7
sce:DAL7
Genes: 1
Protein descriptionDAL7, nitrogenous compound allantoin
Parentonholog:FOG00972
SGD DescriptionMalate synthase; can accept butyryl-CoA as acyl-CoA donor in addition to traditional substrate acetyl-CoA; recycles glyoxylate generated during allantoin degradation; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation
References
Yoo HS, et al. (1989 Aug). The DAL7 promoter consists of multiple elements that cooperatively mediate regulation of the gene's expression.
Hartig A, et al. (1992 Nov 11). Differentially regulated malate synthase genes participate in carbon and nitrogen metabolism of S. cerevisiae.
Fernandez E, et al. (1993 Apr 12). Two structural genes are encoding malate synthase isoenzymes in Saccharomyces cerevisiae.