FOG00906
EOG895XB0

sce:SHB17

Genes: 34

Protein description
Sedoheptulose bisphosphatase involved in riboneogenesis


SGD Description
Sedoheptulose bisphosphatase involved in riboneogenesis; dephosphorylates sedoheptulose 1,7-bisphosphate, which is converted via the nonoxidative pentose phosphate pathway to ribose-5-phosphate; facilitates the conversion of glycolytic intermediates to pentose phosphate units; also has fructose 1,6-bisphosphatase activity but this is probably not biologically relevant, since deletion does not affect FBP levels; GFP-fusion protein localizes to the cytoplasm and nucleus


AspGD Description
Ortholog(s) have sedoheptulose-bisphosphatase activity, role in ribose phosphate biosynthetic process and cytoplasm, nucleus localization|Putative phosphoglycerate mutase


References

Masuo S, et al. (2010 Dec). Global gene expression analysis of Aspergillus nidulans reveals metabolic shift and transcription suppression under hypoxia.

Kuznetsova E, et al. (2010 Jul 2). Structure and activity of the metal-independent fructose-1,6-bisphosphatase YK23 from Saccharomyces cerevisiae.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Clasquin MF, et al. (2011 Jun 10). Riboneogenesis in yeast.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%