FOG00889
EOG8CFXQW
GND1
sce:GND1;GND2

Genes: 35

Protein description
6-phosphogluconate dehydrogenase; some orthologs may localize to [c] and [x] as seen in cal


SGD Description
6-phosphogluconate dehydrogenase (decarboxylating); catalyzes an NADPH regenerating reaction in the pentose phosphate pathway; required for growth on D-glucono-delta-lactone and adaptation to oxidative stress; GND1 has a paralog, GND2, that arose from the whole genome duplication|6-phosphogluconate dehydrogenase (decarboxylating); catalyzes an NADPH regenerating reaction in the pentose phosphate pathway; required for growth on D-glucono-delta-lactone; GND2 has a paralog, GND1, that arose from the whole genome duplication


PomBase Description
phosphogluconate dehydrogenase, decarboxylating


AspGD Description
6-phosphogluconate dehydrogenase, decarboxylating; induced by growth on starch and lactate


Suggested Analysis
Review alternative splicing to determine if [x] is ancestral function or recently gained in cal


References

He W, et al. (2007 Jun 14). Crystal structure of Saccharomyces cerevisiae 6-phosphogluconate dehydrogenase Gnd1.

Malavazi I, et al. (2007 Oct). Transcriptome analysis of the Aspergillus nidulans AtmA (ATM, Ataxia-Telangiectasia mutated) null mutant.

Flipphi M, et al. (2009 Mar). Biodiversity and evolution of primary carbon metabolism in Aspergillus nidulans and other Aspergillus spp.

Sato I, et al. (2009 Mar 20). The glutathione system of Aspergillus nidulans involves a fungus-specific glutathione S-transferase.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Etxebeste O, et al. (2012). GmcA is a putative glucose-methanol-choline oxidoreductase required for the induction of asexual development in Aspergillus nidulans.

Strijbis K, et al. (2012 Feb). Alternative splicing directs dual localization of Candida albicans 6-phosphogluconate dehydrogenase to cytosol and peroxisomes.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG00890
EOG8CFXQW

sce:absent

Genes: 3

AspGD Description
Phosphogluconate dehydrogenase (decarboxylating)

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG00891
EOG8CFXQW

sce:absent

Genes: 1

Parent
onholog?:FOG00889

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%