FOG00818
EOG8RJDK2

sce:VMA10

Genes: 29

Protein description
VATPase.V1.G


SGD Description
Subunit G of the V1 peripheral membrane domain of V-ATPase; part of the electrogenic proton pump found throughout the endomembrane system; involved in vacuolar acidification; the V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase) has eight subunits


AspGD Description
F1F0-ATPase complex subunit


References

Supeková L, et al. (1995 Jun 9). The Saccharomyces cerevisiae VMA10 is an intron-containing gene encoding a novel 13-kDa subunit of vacuolar H(+)-ATPase.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG00819
EOG8RJDK2

sce:SSO1;SSO2

Genes: 38

SGD Description
Plasma membrane t-SNARE; involved in fusion of secretory vesicles at the plasma membrane and in vesicle fusion during sporulation; forms a complex with Sec9p that binds v-SNARE Snc2p; syntaxin homolog; functionally redundant with Sso2p; SSO1 has a paralog, SSO2, that arose from the whole genome duplication|Plasma membrane t-SNARE; involved in fusion of secretory vesicles at the plasma membrane; syntaxin homolog that is functionally redundant with Sso1p; SSO2 has a paralog, SSO1, that arose from the whole genome duplication


PomBase Description
SNARE Psy1


AspGD Description
Predicted plasma membrane t-SNARE involved in vesicular transport


References

Mohamed AH, et al. (1988 Sep 5). Primary structure of the multifunctional alpha subunit protein of yeast fatty acid synthase derived from FAS2 gene sequence.

Aalto MK, et al. (1993 Nov). Yeast syntaxins Sso1p and Sso2p belong to a family of related membrane proteins that function in vesicular transport.

Bernardo SM, et al. (2014 Aug). Secretion and filamentation are mediated by the Candida albicans t-SNAREs Sso2p and Sec9p.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 35 genes with posterior transmembrane prediction > 50%

FOG00820
EOG8RJDK2

sce:SED5

Genes: 34

SGD Description
cis-Golgi t-SNARE syntaxin; required for vesicular transport between the ER and the Golgi complex; binds at least 9 SNARE proteins


PomBase Description
SNARE Sed5 (predicted)


AspGD Description
Ortholog(s) have role in Golgi organization and Golgi apparatus localization


References

Hardwick KG, et al. (1992 Nov). SED5 encodes a 39-kD integral membrane protein required for vesicular transport between the ER and the Golgi complex.

McNew JA, et al. (1998 Sep 11). Gos1p, a Saccharomyces cerevisiae SNARE protein involved in Golgi transport.

Bracher A, et al. (2002 Nov 15). Structural basis for the Golgi membrane recruitment of Sly1p by Sed5p.

Mossessova E, et al. (2003 Aug 22). SNARE selectivity of the COPII coat.

Pantazopoulou A, et al. (2011 Apr). Characterization of Aspergillus nidulans RabC/Rab6.

Pinar M, et al. (2013 Jul). Acute inactivation of the Aspergillus nidulans Golgi membrane fusion machinery: correlation of apical extension arrest and tip swelling with cisternal disorganization.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Hernández-González M, et al. (2015 Feb). Conditional inactivation of Aspergillus nidulans sarA(SAR1) uncovers the morphogenetic potential of regulating endoplasmic reticulum (ER) exit.

López-Berges MS, et al. (2016 Jan). The Aspergillus nidulans syntaxin PepA(Pep12) is regulated by two Sec1/Munc-18 proteins to mediate fusion events at early endosomes, late endosomes and vacuoles.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 33 genes with posterior transmembrane prediction > 50%

FOG00821
EOG8RJDK2

sce:TLG2

Genes: 32

SGD Description
Syntaxin-like t-SNARE; forms a complex with Tlg1p and Vti1p and mediates fusion of endosome-derived vesicles with the late Golgi; binds Vps45p, which prevents Tlg2p degradation and also facilitates t-SNARE complex formation; homologous to mammalian SNARE protein syntaxin 16 (Sx16)


PomBase Description
SNARE Tlg2 (predicted)


AspGD Description
Ortholog(s) have role in positive regulation of cell-substrate adhesion and Golgi cisterna, cytosol, endosome localization


References

Nichols BJ, et al. (1998 Dec). The Sec1p homologue Vps45p binds to the syntaxin Tlg2p.

Abeliovich H, et al. (1998 May 8). Tlg2p, a yeast syntaxin homolog that resides on the Golgi and endocytic structures.

Séron K, et al. (1998 Oct). A yeast t-SNARE involved in endocytosis.

Muthuvijayan V, et al. (2004). In silico reconstruction of nutrient-sensing signal transduction pathways in Aspergillus nidulans.

Wilson-Grady JT, et al. (2008 Mar). Phosphoproteome analysis of fission yeast.

Dixon SJ, et al. (2008 Oct 28). Significant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotes.

Dodgson J, et al. (2009 Aug). Functional genomics of adhesion, invasion, and mycelial formation in Schizosaccharomyces pombe.

Zekert N, et al. (2009 Jan). The Aspergillus nidulans kinesin-3 UncA motor moves vesicles along a subpopulation of microtubules.

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Han TX, et al. (2010). Global fitness profiling of fission yeast deletion strains by barcode sequencing.

Liu NN, et al. (2010 Aug). A genome-wide screen for Schizosaccharomyces pombe deletion mutants that affect telomere length.

Ryuko S, et al. (2012 Aug). Genome-wide screen reveals novel mechanisms for regulating cobalt uptake and detoxification in fission yeast.

Pan X, et al. (2012 Nov 23). Identification of novel genes involved in DNA damage response by screening a genome-wide Schizosaccharomyces pombe deletion library.

Zhou X, et al. (2013). A genome-wide screening of potential target genes to enhance the antifungal activity of micafungin in Schizosaccharomyces pombe.

Pinar M, et al. (2013 Jul). Acute inactivation of the Aspergillus nidulans Golgi membrane fusion machinery: correlation of apical extension arrest and tip swelling with cisternal disorganization.

Anver S, et al. (2014 Aug). Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Graml V, et al. (2014 Oct 27). A genomic Multiprocess survey of machineries that control and link cell shape, microtubule organization, and cell-cycle progression.

Hernández-González M, et al. (2015 Feb). Conditional inactivation of Aspergillus nidulans sarA(SAR1) uncovers the morphogenetic potential of regulating endoplasmic reticulum (ER) exit.

Zhang X, et al. (2015 Oct 9). Characterization of Tamoxifen as an Antifungal Agent Using the Yeast Schizosaccharomyces Pombe Model Organism.

López-Berges MS, et al. (2016 Jan). The Aspergillus nidulans syntaxin PepA(Pep12) is regulated by two Sec1/Munc-18 proteins to mediate fusion events at early endosomes, late endosomes and vacuoles.

Guo L, et al. (2016 Oct 13). Global Fitness Profiling Identifies Arsenic and Cadmium Tolerance Mechanisms in Fission Yeast.

Dudin O, et al. (2017 Apr). A systematic screen for morphological abnormalities during fission yeast sexual reproduction identifies a mechanism of actin aster formation for cell fusion.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 30 genes with posterior transmembrane prediction > 50%

FOG00822
EOG81C5GT
EOG8MCVJ9
EOG8RJDK2

sce:PEP12

Genes: 31

SGD Description
Target membrane receptor (t-SNARE); for vesicular intermediates traveling between the Golgi apparatus and the vacuole; controls entry of biosynthetic, endocytic, and retrograde traffic into the prevacuolar compartment; syntaxin


PomBase Description
SNARE Pep12


AspGD Description
Ortholog(s) have SNAP receptor activity, role in Golgi to vacuole transport, vacuole inheritance and Golgi apparatus, endoplasmic reticulum, fungal-type vacuole membrane, late endosome localization


References

Becherer KA, et al. (1996 Apr). Novel syntaxin homologue, Pep12p, required for the sorting of lumenal hydrolases to the lysosome-like vacuole in yeast.

Reggiori F, et al. (2002 Feb). A transmembrane ubiquitin ligase required to sort membrane proteins into multivesicular bodies.

Takegawa K, et al. (2003 Nov 7). Identification of a SNARE protein required for vacuolar protein transport in Schizosaccharomyces pombe.

Muthuvijayan V, et al. (2004). In silico reconstruction of nutrient-sensing signal transduction pathways in Aspergillus nidulans.

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Calcagno-Pizarelli AM, et al. (2011 Dec 1). Rescue of Aspergillus nidulans severely debilitating null mutations in ESCRT-0, I, II and III genes by inactivation of a salt-tolerance pathway allows examination of ESCRT gene roles in pH signalling.

Rhind N, et al. (2011 May 20). Comparative functional genomics of the fission yeasts.

Hosomi A, et al. (2011 Oct). Schizosaccharomyces pombe Pep12p is required for vacuolar protein transport and vacuolar homotypic fusion.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Beckley JR, et al. (2015 Dec). A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.

Hosomi A, et al. (2015 Jan). Vsl1p cooperates with Fsv1p for vacuolar protein transport and homotypic fusion in Schizosaccharomyces pombe.

López-Berges MS, et al. (2016 Jan). The Aspergillus nidulans syntaxin PepA(Pep12) is regulated by two Sec1/Munc-18 proteins to mediate fusion events at early endosomes, late endosomes and vacuoles.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 31 genes with posterior transmembrane prediction > 50%

FOG00823
EOG8RJDK2

sce:VAM3

Genes: 24

SGD Description
Syntaxin-like vacuolar t-SNARE; functions with Vam7p in vacuolar protein trafficking; mediates docking/fusion of late transport intermediates with the vacuole; has an acidic di-leucine sorting signal and C-terminal transmembrane region


References

Darsow T, et al. (1997 Aug 11). A multispecificity syntaxin homologue, Vam3p, essential for autophagic and biosynthetic protein transport to the vacuole.

Wada Y, et al. (1997 Jun). Vam3p, a new member of syntaxin related protein, is required for vacuolar assembly in the yeast Saccharomyces cerevisiae.

Stefan CJ, et al. (1999 Jan 15). A syntaxin homolog encoded by VAM3 mediates down-regulation of a yeast G protein-coupled receptor.

Dulubova I, et al. (2001 Mar). Vam3p structure reveals conserved and divergent properties of syntaxins.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 24 genes with posterior transmembrane prediction > 50%

FOG00824
EOG8RJDK2

sce:absent

Genes: 2

PomBase Description
V-type ATPase V1 domain subunit G (predicted)


References

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Beckley JR, et al. (2015 Dec). A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG00825
EOG8RJDK2

sce:absent

Genes: 4

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 3 genes with posterior transmembrane prediction > 50%