FOG00793
EOG89GJ3W

sce:TIM11

Genes: 22

Protein description
ATPase.FX.e


SGD Description
Subunit e of mitochondrial F1F0-ATPase; ATPase is a large, evolutionarily conserved enzyme complex required for ATP synthesis; essential for the dimeric and oligomeric state of ATP synthase, which in turn determines the shape of inner membrane cristae


PomBase Description
F0-ATPase subunit E (predicted)


AspGD Description
Ortholog(s) have proton-transporting ATP synthase activity, rotational mechanism, structural molecule activity and role in ATP synthesis coupled proton transport, cristae formation, protein complex oligomerization


References

Arnold I, et al. (1997 Jul 14). Yeast mitochondrial F1F0-ATPase: the novel subunit e is identical to Tim11.

Arnold I, et al. (1998 Dec 15). Yeast mitochondrial F1F0-ATP synthase exists as a dimer: identification of three dimer-specific subunits.

Decottignies A, et al. (2003 Mar). Schizosaccharomyces pombe essential genes: a pilot study.

Tay Z, et al. (2013). Cellular robustness conferred by genetic crosstalk underlies resistance against chemotherapeutic drug doxorubicin in fission yeast.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Nguyen TT, et al. (2015 Feb 11). Fitness profiling links topoisomerase II regulation of centromeric integrity to doxorubicin resistance in fission yeast.

Malecki M, et al. (2016). Identifying genes required for respiratory growth of fission yeast.

Nguyen TT, et al. (2016 Jan 21). Predicting chemotherapeutic drug combinations through gene network profiling.

Malecki M, et al. (2016 Nov 25). Functional and regulatory profiling of energy metabolism in fission yeast.

Lee J, et al. (2017 Feb 20). Chromatin remodeller Fun30<sup>Fft3</sup> induces nucleosome disassembly to facilitate RNA polymerase II elongation.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
8 genes with posterior transmembrane prediction > 50%