FOG00764
EOG81VHQJ

sce:COX17

Genes: 22

Protein description
COX.17.assembly


SGD Description
Copper metallochaperone that transfers copper to Sco1p and Cox11p; eventual delivery to cytochrome c oxidase; contains twin cysteine-x9-cysteine motifs


PomBase Description
cytochrome C oxidase copper chaperone Cox17 (predicted)


AspGD Description
Ortholog(s) have copper chaperone activity, role in intracellular copper ion transport, mitochondrial respiratory chain complex IV assembly and cytosol, mitochondrial intermembrane space, nucleus localization


References

Glerum DM, et al. (1996 Jun 14). Characterization of COX17, a yeast gene involved in copper metabolism and assembly of cytochrome oxidase.

Beers J, et al. (1997 Dec 26). Purification, characterization, and localization of yeast Cox17p, a mitochondrial copper shuttle.

Srinivasan C, et al. (1998 May 19). Characterization of the copper chaperone Cox17 of Saccharomyces cerevisiae.

Abajian C, et al. (2004 Dec 17). Yeast cox17 solution structure and Copper(I) binding.

Malavazi I, et al. (2007 Oct). Transcriptome analysis of the Aspergillus nidulans AtmA (ATM, Ataxia-Telangiectasia mutated) null mutant.

Peter C, et al. (2008 Oct). Copper distributed by Atx1 is available to copper amine oxidase 1 in Schizosaccharomyces pombe.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Chen JS, et al. (2014 Dec 31). Identification of new players in cell division, DNA damage response, and morphogenesis through construction of Schizosaccharomyces pombe deletion strains.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50%