FOG00565
EOG82V72C
GLO1
sce:GLO1

Genes: 35

Protein description
Monomeric glyoxalase I


SGD Description
Monomeric glyoxalase I; catalyzes the detoxification of methylglyoxal (a by-product of glycolysis) via condensation with glutathione to produce S-D-lactoylglutathione; expression regulated by methylglyoxal levels and osmotic stress


PomBase Description
glyoxalase I


AspGD Description
Lactoylglutathione lyase (glyoxylase I)


References

Inoue Y, et al. (1991 Dec). Positive effect of GAC gene product on the mRNA level of glyoxalase I gene in Saccharomyces cerevisiae.

Ridderström M, et al. (1996 Jun 15). The primary structure of monomeric yeast glyoxalase I indicates a gene duplication resulting in two similar segments homologous with the subunit of dimeric human glyoxalase I.

Inoue Y, et al. (1996 Oct 18). Identification of the structural gene for glyoxalase I from Saccharomyces cerevisiae.

Frickel EM, et al. (2001 Jan 19). Yeast glyoxalase I is a monomeric enzyme with two active sites.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%