FOG00284
EOG805QJS
TPI1
sce:TPI1

Genes: 33

Protein description
Triose phosphate isomerase


SGD Description
Triose phosphate isomerase, abundant glycolytic enzyme; mRNA half-life is regulated by iron availability; transcription is controlled by activators Reb1p, Gcr1p, and Rap1p through binding sites in the 5' non-coding region; inhibition of Tpi1p activity by PEP (phosphoenolpyruvate) stimulates redox metabolism in respiring cells; E104D mutation in human TPI causes a rare autosomal disease


PomBase Description
triosephosphate isomerase


AspGD Description
Triose-phosphate-isomerase


References

Alber T, et al. (1981 Feb 10). Crystallization of yeast triose phosphate isomerase from polyethylene glycol. Protein crystal formation following phase separation.

Alber T, et al. (1982). Nucleotide sequence of the triose phosphate isomerase gene of Saccharomyces cerevisiae.

Russell PR, et al. (1985). Transcription of the triose-phosphate-isomerase gene of Schizosaccharomyces pombe initiates from a start point different from that in Saccharomyces cerevisiae.

McKnight GL, et al. (1986 Jul 4). Nucleotide sequence of the triosephosphate isomerase gene from Aspergillus nidulans: implications for a differential loss of introns.

Alber TC, et al. (1987). Crystallography and site-directed mutagenesis of yeast triosephosphate isomerase: what can we learn about catalysis from a "simple" enzyme?

Nikawa J, et al. (1987 Apr 5). Primary structure and disruption of the phosphatidylinositol synthase gene of Saccharomyces cerevisiae.

Lolis E, et al. (1990 Jul 17). Crystallographic analysis of the complex between triosephosphate isomerase and 2-phosphoglycolate at 2.5-A resolution: implications for catalysis.

Lolis E, et al. (1990 Jul 17). Structure of yeast triosephosphate isomerase at 1.9-A resolution.

Lloyd AT, et al. (1991 Nov). Codon usage in Aspergillus nidulans.

Wierenga RK, et al. (1992 Apr 20). Comparison of the refined crystal structures of liganded and unliganded chicken, yeast and trypanosomal triosephosphate isomerase.

Gaynor PM, et al. (1992 Sep). Regulation of CDP-diacylglycerol synthesis and utilization by inositol and choline in Schizosaccharomyces pombe.

Hoyer LL, et al. (2001 Jan 15). The ALS5 gene of Candida albicans and analysis of the Als5p N-terminal domain.

De Backer MD, et al. (2001 Mar). An antisense-based functional genomics approach for identification of genes critical for growth of Candida albicans.

Jogl G, et al. (2003 Jan 7). Optimal alignment for enzymatic proton transfer: structure of the Michaelis complex of triosephosphate isomerase at 1.2-A resolution.

Pitarch A, et al. (2004 Oct). Proteomics-based identification of novel Candida albicans antigens for diagnosis of systemic candidiasis in patients with underlying hematological malignancies.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Chi A, et al. (2007 Feb 13). Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.

Wilson-Grady JT, et al. (2008 Mar). Phosphoproteome analysis of fission yeast.

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Flipphi M, et al. (2009 Mar). Biodiversity and evolution of primary carbon metabolism in Aspergillus nidulans and other Aspergillus spp.

Masuo S, et al. (2010 Dec). Global gene expression analysis of Aspergillus nidulans reveals metabolic shift and transcription suppression under hypoxia.

Oh YT, et al. (2010 Mar). Proteomic analysis of early phase of conidia germination in Aspergillus nidulans.

Singh NS, et al. (2011 Dec 6). SIN-inhibitory phosphatase complex promotes Cdc11p dephosphorylation and propagates SIN asymmetry in fission yeast.

Snaith HA, et al. (2011 Jul 1). Characterization of Mug33 reveals complementary roles for actin cable-dependent transport and exocyst regulators in fission yeast exocytosis.

Etxebeste O, et al. (2012). GmcA is a putative glucose-methanol-choline oxidoreductase required for the induction of asexual development in Aspergillus nidulans.

Starita LM, et al. (2012 Jan). Sites of ubiquitin attachment in Saccharomyces cerevisiae.

Wartenberg D, et al. (2012 Jul 16). Proteome analysis of the farnesol-induced stress response in Aspergillus nidulans--The role of a putative dehydrin.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Duncan CD, et al. (2014 Jul). The translational landscape of fission-yeast meiosis and sporulation.

Beckley JR, et al. (2015 Dec). A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%