FOG00247
EOG89P8D9

sce:RPA135

Genes: 34

Protein description
RNA polymerase


SGD Description
RNA polymerase I second largest subunit A135


PomBase Description
DNA-directed RNA polymerase I complex subunit Rpa2


AspGD Description
DNA-directed RNA polymerase


References

Yano R, et al. (1991 Feb). Suppressor analysis of temperature-sensitive mutations of the largest subunit of RNA polymerase I in Saccharomyces cerevisiae: a suppressor gene encodes the second-largest subunit of RNA polymerase I.

Fath S, et al. (2001 Dec 4). Differential roles of phosphorylation in the formation of transcriptional active RNA polymerase I.

Bischler N, et al. (2002 Aug 1). Localization of the yeast RNA polymerase I-specific subunits.

Van Mullem V, et al. (2002 Mar). Rpa12p, a conserved RNA polymerase I subunit with two functional domains.

Peyroche G, et al. (2002 Nov 12). The A14-A43 heterodimer subunit in yeast RNA pol I and their relationship to Rpb4-Rpb7 pol II subunits.

Naryshkina T, et al. (2003 Oct). Role of second-largest RNA polymerase I subunit Zn-binding domain in enzyme assembly.

Kuhn CD, et al. (2007 Dec 28). Functional architecture of RNA polymerase I.

Furuya K, et al. (2010 Nov 24). DDK phosphorylates checkpoint clamp component Rad9 and promotes its release from damaged chromatin.

Arita Y, et al. (2011 May). Microarray-based target identification using drug hypersensitive fission yeast expressing ORFeome.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Lee NN, et al. (2013 Nov 21). Mtr4-like protein coordinates nuclear RNA processing for heterochromatin assembly and for telomere maintenance.

Engel C, et al. (2013 Oct 31). RNA polymerase I structure and transcription regulation.

Fernández-Tornero C, et al. (2013 Oct 31). Crystal structure of the 14-subunit RNA polymerase I.

Wang J, et al. (2013 Sep 1). Epe1 recruits BET family bromodomain protein Bdf2 to establish heterochromatin boundaries.

Jongjitwimol J, et al. (2014). The S. pombe translation initiation factor eIF4G is Sumoylated and associates with the SUMO protease Ulp2.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Deng L, et al. (2014 Sep 1). Megadalton-node assembly by binding of Skb1 to the membrane anchor Slf1.

Beckley JR, et al. (2015 Dec). A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.

Lee J, et al. (2017 Feb 20). Chromatin remodeller Fun30^Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG00248
EOG89P8D9

sce:RPB2

Genes: 34

Protein description
RNA polymerase


SGD Description
RNA polymerase II second largest subunit B150; part of central core; similar to bacterial beta subunit


PomBase Description
RNA polymerase II complex subunit Rpb2


AspGD Description
DNA-directed RNA polymerase


References

Stunnenberg HG, et al. (1981 Jun). An alpha-amanitin-resistant DNA-dependent RNA polymerase II from the fungus Aspergillus nidulans.

Sweetser D, et al. (1987 Mar). Prokaryotic and eukaryotic RNA polymerases have homologous core subunits.

Riva M, et al. (1990 Sep 25). Mapping the active site of yeast RNA polymerase B (II).

Cramer P, et al. (2001 Jun 8). Structural basis of transcription: RNA polymerase II at 2.8 angstrom resolution.

Gnatt AL, et al. (2001 Jun 8). Structural basis of transcription: an RNA polymerase II elongation complex at 3.3 A resolution.

Bushnell DA, et al. (2002 Feb 5). Structural basis of transcription: alpha-amanitin-RNA polymerase II cocrystal at 2.8 A resolution.

Kettenberger H, et al. (2003 Aug 8). Architecture of the RNA polymerase II-TFIIS complex and implications for mRNA cleavage.

Kurtzman CP, et al. (2003 Jun). Phylogenetic relationships among yeasts of the 'Saccharomyces complex' determined from multigene sequence analyses.

Armache KJ, et al. (2003 Jun 10). Architecture of initiation-competent 12-subunit RNA polymerase II.

Bushnell DA, et al. (2003 Jun 10). Complete, 12-subunit RNA polymerase II at 4.1-A resolution: implications for the initiation of transcription.

Chung WH, et al. (2003 Oct). RNA polymerase II/TFIIF structure and conserved organization of the initiation complex.

Diezmann S, et al. (2004 Dec). Phylogeny and evolution of medical species of Candida and related taxa: a multigenic analysis.

Kettenberger H, et al. (2004 Dec 22). Complete RNA polymerase II elongation complex structure and its interactions with NTP and TFIIS.

Bushnell DA, et al. (2004 Feb 13). Structural basis of transcription: an RNA polymerase II-TFIIB cocrystal at 4.5 Angstroms.

Liu YJ, et al. (2004 Mar 30). Body plan evolution of ascomycetes, as inferred from an RNA polymerase II phylogeny.

Westover KD, et al. (2004 Nov 12). Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center.

Kim M, et al. (2004 Nov 25). The yeast Rat1 exonuclease promotes transcription termination by RNA polymerase II.

Armache KJ, et al. (2005 Feb 25). Structures of complete RNA polymerase II and its subcomplex, Rpb4/7.

Kettenberger H, et al. (2006 Jan). Structure of an RNA polymerase II-RNA inhibitor complex elucidates transcription regulation by noncoding RNAs.

Meyer PA, et al. (2006 Jun). Phasing RNA polymerase II using intrinsically bound Zn atoms: an updated structural model.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG00249
EOG89P8D9

sce:RET1

Genes: 33

Protein description
RNA polymerase


SGD Description
Second-largest subunit of RNA polymerase III; RNA polymerase III is responsible for the transcription of tRNA and 5S RNA genes, and other low molecular weight RNAs


PomBase Description
DNA-directed RNA polymerase III complex subunit Rpc2


AspGD Description
DNA-directed RNA polymerase


References

James P, et al. (1991 Mar 25). The RET1 gene of yeast encodes the second-largest subunit of RNA polymerase III. Structural analysis of the wild-type and ret1-1 mutant alleles.

Chédin S, et al. (1998). The yeast RNA polymerase III transcription machinery: a paradigm for eukaryotic gene activation.

Jasiak AJ, et al. (2006 Jul 7). Structural biology of RNA polymerase III: subcomplex C17/25 X-ray structure and 11 subunit enzyme model.

Yee NS, et al. (2007 Nov). Mutation of RNA Pol III subunit rpc2/polr3b Leads to Deficiency of Subunit Rpc11 and disrupts zebrafish digestive development.

Lemieux C, et al. (2009 Jun). Cotranscriptional recruitment of the nuclear poly(A)-binding protein Pab2 to nascent transcripts and association with translating mRNPs.

Pancaldi V, et al. (2012 Apr). Predicting the fission yeast protein interaction network.

Wang J, et al. (2013 Sep 1). Epe1 recruits BET family bromodomain protein Bdf2 to establish heterochromatin boundaries.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Legros P, et al. (2014 Nov). RNA processing factors Swd2.2 and Sen1 antagonize RNA Pol III-dependent transcription and the localization of condensin at Pol III genes.

Beckley JR, et al. (2015 Dec). A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.

McDonald KR, et al. (2016 Sep). Pfh1 Is an Accessory Replicative Helicase that Interacts with the Replisome to Facilitate Fork Progression and Preserve Genome Integrity.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 4 genes with posterior transmembrane prediction > 50%