FOG00237
EOG83TXDC

sce:RPB5

Genes: 33

Protein description
RNA polymerase


SGD Description
RNA polymerase subunit ABC27; common to RNA polymerases I, II, and III; contacts DNA and affects transactivation


PomBase Description
DNA-directed RNA polymerase I, II and III subunit Rpb5


AspGD Description
DNA-directed RNA polymerase


References

Woychik NA, et al. (1990 Mar). Subunits shared by eukaryotic nuclear RNA polymerases.

Miyao T, et al. (1996 Sep). Molecular assembly of RNA polymerase II from the fission yeast Schizosaccharomyces pombe: subunit-subunit contact network involving Rpb5.

Shpakovskiĭ GV, et al. (1997 Dec). [Molecular cloning of rpb5+, rpb7+ and rpb11+ genes of the fission yeast Schizosaccharomyces pombe: completing primary structure of all indispensable subunits of its RNA polymerase II].

Kimura M, et al. (1997 Oct 10). RNA polymerase II subunits 2, 3, and 11 form a core subassembly with DNA binding activity.

Sakurai H, et al. (1997 Sep 1). Gene organization and protein sequence of the small subunits of Schizosaccharomyces pombe RNA polymerase II.

Chédin S, et al. (1998). The yeast RNA polymerase III transcription machinery: a paradigm for eukaryotic gene activation.

Yasui K, et al. (1998 Apr 21). Location of subunit-subunit contact sites on RNA polymerase II subunit 3 from the fission yeast Schizosaccharomyces pombe.

Miyao T, et al. (1998 Jul). Mapping of Rpb3 and Rpb5 contact sites on two large subunits, Rpb1 and Rpb2, of the RNA polymerase II from fission yeast.

Ishiguro A, et al. (1998 Jun 19). Two large subunits of the fission yeast RNA polymerase II provide platforms for the assembly of small subunits.

Mitobe J, et al. (1999 Aug). Isolation and characterization of temperature-sensitive mutations in the gene (rpb3) for subunit 3 of RNA polymerase II in the fission yeast Schizosaccharomyces pombe.

Kimura M, et al. (2000 Feb 15). Involvement of multiple subunit-subunit contacts in the assembly of RNA polymerase II.

Shpakovski GV, et al. (2000 Feb 4). Functional conservation of RNA polymerase II in fission and budding yeasts.

Spåhr H, et al. (2000 Jan 14). Purification and characterization of RNA polymerase II holoenzyme from Schizosaccharomyces pombe.

Todone F, et al. (2000 Jun 6). Crystal structure of RPB5, a universal eukaryotic RNA polymerase subunit and transcription factor interaction target.

Fath S, et al. (2001 Dec 4). Differential roles of phosphorylation in the formation of transcriptional active RNA polymerase I.

Kimura M, et al. (2001 Feb). Intracellular contents and assembly states of all 12 subunits of the RNA polymerase II in the fission yeast Schizosaccharomyces pombe.

Cramer P, et al. (2001 Jun 8). Structural basis of transcription: RNA polymerase II at 2.8 angstrom resolution.

Gnatt AL, et al. (2001 Jun 8). Structural basis of transcription: an RNA polymerase II elongation complex at 3.3 A resolution.

Bushnell DA, et al. (2002 Feb 5). Structural basis of transcription: alpha-amanitin-RNA polymerase II cocrystal at 2.8 A resolution.

Kimura M, et al. (2002 Mar). Formation of a carboxy-terminal domain phosphatase (Fcp1)/TFIIF/RNA polymerase II (pol II) complex in Schizosaccharomyces pombe involves direct interaction between Fcp1 and the Rpb4 subunit of pol II.

Sakurai H, et al. (2002 Mar). Level of the RNA polymerase II in the fission yeast stays constant but phosphorylation of its carboxyl terminal domain varies depending on the phase and rate of cell growth.

Van Mullem V, et al. (2002 Mar). Rpa12p, a conserved RNA polymerase I subunit with two functional domains.

Peyroche G, et al. (2002 Nov 12). The A14-A43 heterodimer subunit in yeast RNA pol I and their relationship to Rpb4-Rpb7 pol II subunits.

Kettenberger H, et al. (2003 Aug 8). Architecture of the RNA polymerase II-TFIIS complex and implications for mRNA cleavage.

Armache KJ, et al. (2003 Jun 10). Architecture of initiation-competent 12-subunit RNA polymerase II.

Bushnell DA, et al. (2003 Jun 10). Complete, 12-subunit RNA polymerase II at 4.1-A resolution: implications for the initiation of transcription.

Chung WH, et al. (2003 Oct). RNA polymerase II/TFIIF structure and conserved organization of the initiation complex.

Kettenberger H, et al. (2004 Dec 22). Complete RNA polymerase II elongation complex structure and its interactions with NTP and TFIIS.

Bushnell DA, et al. (2004 Feb 13). Structural basis of transcription: an RNA polymerase II-TFIIB cocrystal at 4.5 Angstroms.

Tamayo E, et al. (2004 Jun). Mediator is required for activated transcription in a Schizosaccharomyces pombe in vitro system.

Westover KD, et al. (2004 Nov 12). Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center.

Armache KJ, et al. (2005 Feb 25). Structures of complete RNA polymerase II and its subcomplex, Rpb4/7.

Hayashi K, et al. (2005 Mar). Studies of Schizosaccharomyces pombe TFIIE indicate conformational and functional changes in RNA polymerase II at transcription initiation.

Djupedal I, et al. (2005 Oct 1). RNA Pol II subunit Rpb7 promotes centromeric transcription and RNAi-directed chromatin silencing.

Kettenberger H, et al. (2006 Jan). Structure of an RNA polymerase II-RNA inhibitor complex elucidates transcription regulation by noncoding RNAs.

Jasiak AJ, et al. (2006 Jul 7). Structural biology of RNA polymerase III: subcomplex C17/25 X-ray structure and 11 subunit enzyme model.

Meyer PA, et al. (2006 Jun). Phasing RNA polymerase II using intrinsically bound Zn atoms: an updated structural model.

Kuhn CD, et al. (2007 Dec 28). Functional architecture of RNA polymerase I.

Wilson-Grady JT, et al. (2008 Mar). Phosphoproteome analysis of fission yeast.

Spåhr H, et al. (2009 Jun 9). Schizosacharomyces pombe RNA polymerase II at 3.6-A resolution.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Freitas JS, et al. (2011 Sep). Transcription of the Hsp30, Hsp70, and Hsp90 heat shock protein genes is modulated by the PalA protein in response to acid pH-sensing in the fungus Aspergillus nidulans.

Engel C, et al. (2013 Oct 31). RNA polymerase I structure and transcription regulation.

Fernández-Tornero C, et al. (2013 Oct 31). Crystal structure of the 14-subunit RNA polymerase I.

Wang J, et al. (2013 Sep 1). Epe1 recruits BET family bromodomain protein Bdf2 to establish heterochromatin boundaries.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Suzuki S, et al. (2014 May). A novel method for purification of the endogenously expressed fission yeast Set2 complex.

Beckley JR, et al. (2015 Dec). A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.

Suzuki S, et al. (2016 May 19). Histone H3K36 trimethylation is essential for multiple silencing mechanisms in fission yeast.

Lee J, et al. (2017 Feb 20). Chromatin remodeller Fun30^Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%