FOG00135
EOG8SJ41D
MRPL25
sce:MRPL25

Genes: 31

Protein description
MRPL25 Mitochondrial large ribosome protein subunit


SGD Description
Mitochondrial ribosomal protein of the large subunit; mutation confers increased replicative lifespan


PomBase Description
mitochondrial ribosomal protein subunit L25 (predicted)


AspGD Description
Protein of unknown function


References

Grohmann L, et al. (1991 Jun 17). Extended N-terminal sequencing of proteins of the large ribosomal subunit from yeast mitochondria.

Kang W, et al. (1991 Mar). Cloning and analysis of YMR26, the nuclear gene for a mitochondrial ribosomal protein in Saccharomyces cerevisiae.

Gan X, et al. (2002 Nov). Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components.

Sickmann A, et al. (2003 Nov 11). The proteome of Saccharomyces cerevisiae mitochondria.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Amunts A, et al. (2014 Mar 28). Structure of the yeast mitochondrial large ribosomal subunit.

Pfeffer S, et al. (2015 Jan 22). Organization of the mitochondrial translation machinery studied in situ by cryoelectron tomography.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG00136
EOG8G4F9P
EOG8SJ41D

sce:absent

Genes: 9

Protein description
diphthamide biosynthesis protein Dph4 (predicted)


PomBase Description
diphthamide biosynthesis protein Dph4 (predicted)


AspGD Description
Ortholog(s) have ferrous iron binding activity, role in peptidyl-diphthamide biosynthetic process from peptidyl-histidine and cytosol, nucleus localization


References

Chen ES, et al. (2003 Jan). A cell cycle-regulated GATA factor promotes centromeric localization of CENP-A in fission yeast.

Yuasa T, et al. (2004 Nov). An interactive gene network for securin-separase, condensin, cohesin, Dis1/Mtc1 and histones constructed by mass transformation.

Sanders SL, et al. (2004 Nov 24). Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage.

Takahashi K, et al. (2005 Mar 29). Two distinct pathways responsible for the loading of CENP-A to centromeres in the fission yeast cell cycle.

Nishijima H, et al. (2006 Jun). Nuclear RanGAP is required for the heterochromatin assembly and is reciprocally regulated by histone H3 and Clr4 histone methyltransferase in Schizosaccharomyces pombe.

Takayama Y, et al. (2007). Differential regulation of repeated histone genes during the fission yeast cell cycle.

Hortschansky P, et al. (2007 Jul 11). Interaction of HapX with the CCAAT-binding complex--a novel mechanism of gene regulation by iron.

Stuwe T, et al. (2008 Jul 1). The FACT Spt16 "peptidase" domain is a histone H3-H4 binding module.

Han TX, et al. (2010). Global fitness profiling of fission yeast deletion strains by barcode sequencing.

Keller C, et al. (2010 Jun). Proteomic and functional analysis of the noncanonical poly(A) polymerase Cid14.

Takayama Y, et al. (2010 Mar 16). Hsk1- and SCF(Pof3)-dependent proteolysis of S. pombe Ams2 ensures histone homeostasis and centromere function.

Takeda K, et al. (2011). Identification of genes affecting the toxicity of anti-cancer drug bortezomib by genome-wide screening in S. pombe.

Yamane K, et al. (2011 Jan 7). Asf1/HIRA facilitate global histone deacetylation and associate with HP1 to promote nucleosome occupancy at heterochromatic loci.

Snaith HA, et al. (2011 Jul 1). Characterization of Mug33 reveals complementary roles for actin cable-dependent transport and exocyst regulators in fission yeast exocytosis.

Pancaldi V, et al. (2012 Apr). Predicting the fission yeast protein interaction network.

Garabedian MV, et al. (2012 Feb). The double-bromodomain proteins Bdf1 and Bdf2 modulate chromatin structure to regulate S-phase stress response in Schizosaccharomyces pombe.

Qiu Y, et al. (2012 Mar 15). Solution structure of the Pdp1 PWWP domain reveals its unique binding sites for methylated H4K20 and DNA.

Tong K, et al. (2012 Sep). Schizosaccharomyces pombe Hat1 (Kat1) is associated with Mis16 and is required for telomeric silencing.

Kunoh T, et al. (2014). Pcf1, a large subunit of CAF-1, required for maintenance of checkpoint kinase Cds1 activity.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Zilio N, et al. (2014 Sep 15). A novel histone deacetylase complex in the control of transcription and genome stability.

Beckley JR, et al. (2015 Dec). A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.

Gal C, et al. (2016 Jan). Abo1, a conserved bromodomain AAA-ATPase, maintains global nucleosome occupancy and organisation.

Lee J, et al. (2017 Feb 20). Chromatin remodeller Fun30^Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%