FOG00090
EOG8STQRF
RPS19
sce:RPS19A;RPS19B

Genes: 31

Protein description
RPS19 Small ribosome protein subunit


SGD Description
Protein component of the small (40S) ribosomal subunit; required for assembly and maturation of pre-40 S particles; homologous to mammalian ribosomal protein S19, no bacterial homolog; mutations in human RPS19 are associated with Diamond Blackfan anemia; RPS19A has a paralog, RPS19B, that arose from the whole genome duplication|Protein component of the small (40S) ribosomal subunit; required for assembly and maturation of pre-40 S particles; homologous to mammalian ribosomal protein S19, no bacterial homolog; mutations in human RPS19 are associated with Diamond Blackfan anemia; RPS19B has a paralog, RPS19A, that arose from the whole genome duplication


PomBase Description
40S ribosomal protein S19 (predicted)


AspGD Description
Ortholog(s) have structural constituent of ribosome activity, role in rRNA export from nucleus, ribosomal small subunit biogenesis and cytosolic small ribosomal subunit, nucleolus localization


References

Otaka E, et al. (1982 Sep 14). Isolation of seventeen proteins and amino-terminal amino acid sequences of eight proteins from cytoplasmic ribosomes of yeast.

Molenaar CM, et al. (1984 Oct 11). Structure and organization of two linked ribosomal protein genes in yeast.

Bradshaw RE, et al. (1991 Dec 1). Isolation and nucleotide sequence of the ribosomal protein S16-encoding gene from Aspergillus nidulans.

Planta RJ, et al. (1998 Mar 30). The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Arnold RJ, et al. (1999 Dec 24). The action of N-terminal acetyltransferases on yeast ribosomal proteins.

Jeong HY, et al. (2001 Jan 10). Differential expression of house-keeping genes of Aspergillus nidulans during sexual development.

Léger-Silvestre I, et al. (2005 Nov 18). Specific Role for Yeast Homologs of the Diamond Blackfan Anemia-associated Rps19 Protein in Ribosome Synthesis.

Gregory LA, et al. (2007). Molecular basis of Diamond-Blackfan anemia: structure and function analysis of RPS19.

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Ben-Shem A, et al. (2010 Nov 26). Crystal structure of the eukaryotic ribosome.

Ben-Shem A, et al. (2011 Dec 16). The structure of the eukaryotic ribosome at 3.0 Å resolution.

Nie M, et al. (2012 Aug 24). Dual recruitment of Cdc48 (p97)-Ufd1-Npl4 ubiquitin-selective segregase by small ubiquitin-like modifier protein (SUMO) and ubiquitin in SUMO-targeted ubiquitin ligase-mediated genome stability functions.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Ban N, et al. (2014 Feb). A new system for naming ribosomal proteins.

Hussain T, et al. (2014 Oct 23). Structural changes enable start codon recognition by the eukaryotic translation initiation complex.

Mathiassen SG, et al. (2015 Aug 21). A Two-step Protein Quality Control Pathway for a Misfolded DJ-1 Variant in Fission Yeast.

Llácer JL, et al. (2015 Aug 6). Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex.

Beckley JR, et al. (2015 Dec). A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.

Murray J, et al. (2016 May 9). Structural characterization of ribosome recruitment and translocation by type IV IRES.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%