FOG00042
EOG81G1KF
EOG83TXFH
RPL28
sce:RPL28

Genes: 34

Protein description
RPL28 Large ribosome protein subunit


SGD Description
Ribosomal 60S subunit protein L28; homologous to mammalian ribosomal protein L27A and bacterial L15; may have peptidyl transferase activity; can mutate to cycloheximide resistance


PomBase Description
60S ribosomal protein L27/L28


AspGD Description
Ortholog(s) have RNA binding activity and cytosolic large ribosomal subunit, mitochondrion, nucleus, preribosome, large subunit precursor localization


References

Käufer NF, et al. (1983 May 25). Cycloheximide resistance in yeast: the gene and its protein.

Schwindinger WF, et al. (1987 Apr 25). Transcriptional elements of the yeast ribosomal protein gene CYH2.

Underwood MR, et al. (1990 Jan). Characterization of nuclear localizing sequences derived from yeast ribosomal protein L29.

Planta RJ, et al. (1998 Mar 30). The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Arnold RJ, et al. (1999 Dec 24). The action of N-terminal acetyltransferases on yeast ribosomal proteins.

Spahn CM, et al. (2001 Nov 2). Structure of the 80S ribosome from Saccharomyces cerevisiae--tRNA-ribosome and subunit-subunit interactions.

Spahn CM, et al. (2004 Mar 10). Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation.

Keller C, et al. (2010 Jun). Proteomic and functional analysis of the noncanonical poly(A) polymerase Cid14.

Ben-Shem A, et al. (2010 Nov 26). Crystal structure of the eukaryotic ribosome.

Takeda K, et al. (2011). Identification of genes affecting the toxicity of anti-cancer drug bortezomib by genome-wide screening in S. pombe.

Ben-Shem A, et al. (2011 Dec 16). The structure of the eukaryotic ribosome at 3.0 Å resolution.

Snaith HA, et al. (2011 Jul 1). Characterization of Mug33 reveals complementary roles for actin cable-dependent transport and exocyst regulators in fission yeast exocytosis.

Freitas JS, et al. (2011 Sep). Transcription of the Hsp30, Hsp70, and Hsp90 heat shock protein genes is modulated by the PalA protein in response to acid pH-sensing in the fungus Aspergillus nidulans.

Starita LM, et al. (2012 Jan). Sites of ubiquitin attachment in Saccharomyces cerevisiae.

Anver S, et al. (2014 Aug). Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Ban N, et al. (2014 Feb). A new system for naming ribosomal proteins.

Beckley JR, et al. (2015 Dec). A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.

Dudin O, et al. (2017 Apr). A systematic screen for morphological abnormalities during fission yeast sexual reproduction identifies a mechanism of actin aster formation for cell fusion.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG00043
EOG81G1KF

sce:CHL1

Genes: 32

Protein description
Probable DNA helicase


SGD Description
Probable DNA helicase; involved in sister-chromatid cohesion and genome integrity and interstrand cross-link repair; interacts with ECO1 and CTF18; mutants are defective in silencing, rDNA recombination, aging and the heat shock response; FANCJ-like helicase family member; mutations in the human homolog, DDX11/ChLR1, cause Warsaw breakage syndrome


PomBase Description
ATP-dependent DNA helicase Chl1 (predicted)


AspGD Description
Ortholog(s) have cytosol, nucleus, site of double-strand break localization


Suggested Analysis
Likely a spurious homolog


References

Gerring SL, et al. (1990 Dec). The CHL 1 (CTF 1) gene product of Saccharomyces cerevisiae is important for chromosome transmission and normal cell cycle progression in G2/M.

L Holloway S, et al. (2000 Aug 15). CHL1 is a nuclear protein with an essential ATP binding site that exhibits a size-dependent effect on chromosome segregation.

Mayer ML, et al. (2004 Apr). Identification of protein complexes required for efficient sister chromatid cohesion.

Skibbens RV, et al. (2004 Jan). Chl1p, a DNA helicase-like protein in budding yeast, functions in sister-chromatid cohesion.

Petronczki M, et al. (2004 Jul 15). Sister-chromatid cohesion mediated by the alternative RF-CCtf18/Dcc1/Ctf8, the helicase Chl1 and the polymerase-alpha-associated protein Ctf4 is essential for chromatid disjunction during meiosis II.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 5 genes with posterior transmembrane prediction > 50%