FOG00021
EOG8GF20R
RPL17
sce:RPL17A;RPL17B

Genes: 35

Protein description
RPL17 Large ribosome protein subunit


SGD Description
Ribosomal 60S subunit protein L17A; copurifies with the Dam1 complex (aka DASH complex); homologous to mammalian ribosomal protein L17 and bacterial L22; RPL17A has a paralog, RPL17B, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress|Ribosomal 60S subunit protein L17B; homologous to mammalian ribosomal protein L17 and bacterial L22; RPL17B has a paralog, RPL17A, that arose from the whole genome duplication


PomBase Description
60S ribosomal protein L17|60S ribosomal protein L17 (predicted)


AspGD Description
Ortholog(s) have structural constituent of ribosome activity, role in cellular response to drug, cytoplasmic translation and cell surface, cytosolic large ribosomal subunit, extracellular region localization


References

Otaka E, et al. (1984). Yeast ribosomal proteins. VIII. Isolation of two proteins and sequence characterization of twenty-four proteins from cytoplasmic ribosomes.

Planta RJ, et al. (1998 Mar 30). The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Arnold RJ, et al. (1999 Dec 24). The action of N-terminal acetyltransferases on yeast ribosomal proteins.

Spahn CM, et al. (2001 Nov 2). Structure of the 80S ribosome from Saccharomyces cerevisiae--tRNA-ribosome and subunit-subunit interactions.

Tallada VA, et al. (2002 Sep 30). Genome-wide search of Schizosaccharomyces pombe genes causing overexpression-mediated cell cycle defects.

Spahn CM, et al. (2004 Mar 10). Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation.

Alvarez B, et al. (2006 Nov 1). Fission yeast Tor2 promotes cell growth and represses cell differentiation.

Chi A, et al. (2007 Feb 13). Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Ben-Shem A, et al. (2010 Nov 26). Crystal structure of the eukaryotic ribosome.

Ben-Shem A, et al. (2011 Dec 16). The structure of the eukaryotic ribosome at 3.0 Å resolution.

Starita LM, et al. (2012 Jan). Sites of ubiquitin attachment in Saccharomyces cerevisiae.

Saykhedkar S, et al. (2012 Jul 26). A time course analysis of the extracellular proteome of Aspergillus nidulans growing on sorghum stover.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Ban N, et al. (2014 Feb). A new system for naming ribosomal proteins.

Lipp JJ, et al. (2015 Aug). SR protein kinases promote splicing of nonconsensus introns.

Mathiassen SG, et al. (2015 Aug 21). A Two-step Protein Quality Control Pathway for a Misfolded DJ-1 Variant in Fission Yeast.

Beckley JR, et al. (2015 Dec). A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.

Murray J, et al. (2016 May 9). Structural characterization of ribosome recruitment and translocation by type IV IRES.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG00022
EOG8GF20R
GOR1
sce:GOR1

Genes: 41

Protein description
Glyoxylate reductase


Parent
paralog?:FOG00021


SGD Description
Glyoxylate reductase; null mutation results in increased biomass after diauxic shift; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; protein abundance increases in response to DNA replication stress


PomBase Description
glyoxylate reductase (predicted)


AspGD Description
Ortholog(s) have extracellular region localization|Ortholog(s) have cytosol, nucleus localization|Has domain(s) with predicted NAD binding, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor activity and role in oxidation-reduction process


Suggested Analysis
Multiple sequence alignment shows this ortholog is poorly aligned to RL17 sequence. Could be an ancient paralog or spurious homolog assignment.


References

Sickmann A, et al. (2003 Nov 11). The proteome of Saccharomyces cerevisiae mitochondria.

Reinders J, et al. (2006 Jul). Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

Rintala E, et al. (2007 Feb). The ORF YNL274c (GOR1) codes for glyoxylate reductase in Saccharomyces cerevisiae.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG00023
EOG8GF20R

sce:absent

Genes: 2

Protein description
Uncharacterized protein similar to RPL17


Parent
paralog:FOG00022


Suggested Analysis
Check for convergent evolution between dha and wan, or presence of a xenolog

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG00024
EOG8GF20R

sce:absent

Genes: 1

Protein description
Uncharacterized protein similar to RPL17


Parent
paralog:FOG00022


PomBase Description
glyoxylate reductase (predicted)


References

Chen D, et al. (2003 Jan). Global transcriptional responses of fission yeast to environmental stress.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Rallis C, et al. (2014 Feb 15). Systematic screen for mutants resistant to TORC1 inhibition in fission yeast reveals genes involved in cellular ageing and growth.

Dudin O, et al. (2017 Apr). A systematic screen for morphological abnormalities during fission yeast sexual reproduction identifies a mechanism of actin aster formation for cell fusion.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%