FOG00014
EOG8V41TJ
RPL12
sce:RPL12A;RPL12B

Genes: 36

Protein description
RPL12 Large ribosome protein subunit


SGD Description
Ribosomal 60S subunit protein L12A; rpl12a rpl12b double mutant exhibits slow growth and slow translation; homologous to mammalian ribosomal protein L12 and bacterial L11; RPL12A has a paralog, RPL12B, that arose from the whole genome duplication|Ribosomal 60S subunit protein L12B; rpl12a rpl12b double mutant exhibits slow growth and slow translation; homologous to mammalian ribosomal protein L12 and bacterial L11; RPL12B has a paralog, RPL12A, that arose from the whole genome duplication


PomBase Description
60S ribosomal protein L12.1/L12A


AspGD Description
Ortholog(s) have role in ribosomal large subunit assembly and cytosolic large ribosomal subunit, nucleolus, preribosome, large subunit precursor localization


References

Otaka E, et al. (1984). Yeast ribosomal proteins. VIII. Isolation of two proteins and sequence characterization of twenty-four proteins from cytoplasmic ribosomes.

Pucciarelli MG, et al. (1990 Aug 11). The 26S rRNA binding ribosomal protein equivalent to bacterial protein L11 is encoded by unspliced duplicated genes in Saccharomyces cerevisiae.

Planta RJ, et al. (1998 Mar 30). The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.

Spahn CM, et al. (2001 Nov 2). Structure of the 80S ribosome from Saccharomyces cerevisiae--tRNA-ribosome and subunit-subunit interactions.

Lee SW, et al. (2002 Apr 30). Direct mass spectrometric analysis of intact proteins of the yeast large ribosomal subunit using capillary LC/FTICR.

Chern MK, et al. (2002 May 3). Yeast ribosomal protein L12 is a substrate of protein-arginine methyltransferase 2.

Spahn CM, et al. (2004 Mar 10). Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation.

Porras-Yakushi TR, et al. (2006 Nov 24). A novel SET domain methyltransferase in yeast: Rkm2-dependent trimethylation of ribosomal protein L12ab at lysine 10.

Shirai A, et al. (2008 Apr 18). Global analysis of gel mobility of proteins and its use in target identification.

Webb KJ, et al. (2008 Dec 19). Identification of two SET domain proteins required for methylation of lysine residues in yeast ribosomal protein Rpl42ab.

Sadaie M, et al. (2008 Mar 14). A conserved SET domain methyltransferase, Set11, modifies ribosomal protein Rpl12 in fission yeast.

Lemieux C, et al. (2009 Jun). Cotranscriptional recruitment of the nuclear poly(A)-binding protein Pab2 to nascent transcripts and association with translating mRNPs.

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Paul SK, et al. (2009 Sep). A large complex mediated by Moc1, Moc2 and Cpc2 regulates sexual differentiation in fission yeast.

Webb KJ, et al. (2010 Jun 29). Identification of protein N-terminal methyltransferases in yeast and humans.

Ben-Shem A, et al. (2010 Nov 26). Crystal structure of the eukaryotic ribosome.

Stewart EV, et al. (2011 Apr 22). Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Ben-Shem A, et al. (2011 Dec 16). The structure of the eukaryotic ribosome at 3.0 Å resolution.

Starita LM, et al. (2012 Jan). Sites of ubiquitin attachment in Saccharomyces cerevisiae.

Das J, et al. (2013 May 21). Cross-species protein interactome mapping reveals species-specific wiring of stress response pathways.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Sideri T, et al. (2014 Dec 1). Parallel profiling of fission yeast deletion mutants for proliferation and for lifespan during long-term quiescence.

Ban N, et al. (2014 Feb). A new system for naming ribosomal proteins.

Chen W, et al. (2014 Mar). Endogenous U2·U5·U6 snRNA complexes in S. pombe are intron lariat spliceosomes.

Mathiassen SG, et al. (2015 Aug 21). A Two-step Protein Quality Control Pathway for a Misfolded DJ-1 Variant in Fission Yeast.

Beckley JR, et al. (2015 Dec). A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.

Nie M, et al. (2015 Sep 25). High Confidence Fission Yeast SUMO Conjugates Identified by Tandem Denaturing Affinity Purification.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG00015
EOG8V41TJ

sce:absent

Genes: 1

Protein description
Uncharacterized ohnolog of RPL12


Parent
ohnlog?:FOG00014

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%